MYLK3 Antibody
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中文名稱：MYLK3兔多克隆抗體
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貨號：CSB-PA015322GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：caMLCK antibody; cardiac MLCK antibody; Cardiac MyBP C associated Ca/CaM kinase antibody; Cardiac-MyBP-C-associated Ca/CaM kinase antibody; MLC kinase antibody; MLCK antibody; MLCK2 antibody; Mylk3 antibody; MYLK3_HUMAN antibody; Myosin light chain kinase 3 antibody; Putative myosin light chain kinase 3 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Human MYLK3
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility.
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基因功能參考文獻：
- This study demonstrates that cyclic stretch disrupts tight junctions and adherens junctions by a JNK2, c-Src, and MLCK-dependent mechanism. PMID: 24722904
- Biochemical and physiological regulation of cardiac myocyte contraction by cardiac-specific myosin light chain kinase. PMID: 23863751
- These findings suggest that hepatitis B virus X protein disrupts stress fiber formation and triggers apoptosis via an MLCK and a PTEN-dependent pathway. PMID: 23591626
- Integrated cDNA expression analysis of failing human myocardia uncovered a novel protein kinase, cardiac-specific myosin light chain kinase (cardiac-MLCK), which acts on MLC2v. PMID: 17885681
- data indicate that the IL-1beta-induced increase in MLCK protein expression and Caco-2 TJ permeability was mediated by an increase in MLCK expression and activity and by an NF-kappaB-dependent increase in MLCK gene transcription PMID: 18390750
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亞細胞定位：Cytoplasm.
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蛋白家族：Protein kinase superfamily, CAMK Ser/Thr protein kinase family
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組織特異性：Restricted to heart.
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數據庫鏈接：
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