MID2 Antibody
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中文名稱：MID2兔多克隆抗體
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貨號：CSB-PA892324ESR1HU
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規格：￥440
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圖片：
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Western blot
All lanes: MID2 antibody at 3.32 μg/ml + Mouse small intestine tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 84, 80 kDa
Observed band size: 84, 30 kDa -
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA892324ESR1HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA892324ESR1HU at dilution of 1:100 -
Immunofluorescent analysis of MCF-7 cells using CSB-PA892324ESR1HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) MID2 Polyclonal antibody
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Uniprot No.：
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基因名：MID2
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別名：FLJ37715 antibody; FLJ41813 antibody; FXY2 antibody; MID2 antibody; Midin 2 antibody; Midin-2 antibody; Midline 2 antibody; Midline defect 2 antibody; Midline-2 antibody; probable E3 ubiquitin protein ligase MID2 antibody; Probable E3 ubiquitin-protein ligase MID2 antibody; RING finger protein 60 antibody; Ring finger protein protein 60 antibody; RNF60 antibody; TRIM1 antibody; TRIM1_HUMAN antibody; tripartite motif containing protein 1 antibody; Tripartite motif protein 1 antibody; Tripartite motif-containing protein 1 antibody
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宿主：Rabbit
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反應種屬：Human, Mouse
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免疫原：Recombinant Human Probable E3 ubiquitin-protein ligase MID2 protein (506-735AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC, IF
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:20-1:200 IF 1:50-1:200 -
Protocols：
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May play a role in microtubule stabilization.
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基因功能參考文獻：
- overexpressed in advanced breast cancer and high overexpression is prognostic factor for poor overall survival PMID: 26791755
- Mid2 regulates cell division through the ubiquitination of astrin on K409, which is critical for its degradation and proper cytokinesis. PMID: 26748699
- A novel missense mutation (c.1040G>A, p.Arg347Gln) was reported in MID2, which encodes ubiquitin ligase E3, as the likely cause of X-linked mental retardation in a large kindred. PMID: 24115387
- MID2 coiled-coil motifs mediate both homo- and heterodimerization, a prerequisite for association of the MID-alpha 4 complex with microtubules. PMID: 11806752
- MID2 is a candidate gene for FG syndrome. PMID: 16283679
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相關疾病：Mental retardation, X-linked 101 (MRX101)
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亞細胞定位：Cytoplasm. Cytoplasm, cytoskeleton. Note=Microtubule-associated.
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蛋白家族：TRIM/RBCC family
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組織特異性：Low level in fetal kidney and lung, and in adult prostate, ovary and small intestine.
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數據庫鏈接：
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