MID2 Antibody
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中文名稱：MID2兔多克隆抗體
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貨號：CSB-PA013821GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：MID2
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別名：FLJ37715 antibody; FLJ41813 antibody; FXY2 antibody; MID2 antibody; Midin 2 antibody; Midin-2 antibody; Midline 2 antibody; Midline defect 2 antibody; Midline-2 antibody; probable E3 ubiquitin protein ligase MID2 antibody; Probable E3 ubiquitin-protein ligase MID2 antibody; RING finger protein 60 antibody; Ring finger protein protein 60 antibody; RNF60 antibody; TRIM1 antibody; TRIM1_HUMAN antibody; tripartite motif containing protein 1 antibody; Tripartite motif protein 1 antibody; Tripartite motif-containing protein 1 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human MID2
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：May play a role in microtubule stabilization.
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基因功能參考文獻(xiàn)：
- overexpressed in advanced breast cancer and high overexpression is prognostic factor for poor overall survival PMID: 26791755
- Mid2 regulates cell division through the ubiquitination of astrin on K409, which is critical for its degradation and proper cytokinesis. PMID: 26748699
- A novel missense mutation (c.1040G>A, p.Arg347Gln) was reported in MID2, which encodes ubiquitin ligase E3, as the likely cause of X-linked mental retardation in a large kindred. PMID: 24115387
- MID2 coiled-coil motifs mediate both homo- and heterodimerization, a prerequisite for association of the MID-alpha 4 complex with microtubules. PMID: 11806752
- MID2 is a candidate gene for FG syndrome. PMID: 16283679
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相關(guān)疾病：Mental retardation, X-linked 101 (MRX101)
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亞細(xì)胞定位：Cytoplasm. Cytoplasm, cytoskeleton. Note=Microtubule-associated.
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蛋白家族：TRIM/RBCC family
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組織特異性：Low level in fetal kidney and lung, and in adult prostate, ovary and small intestine.
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數(shù)據(jù)庫鏈接：
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