LMO4 Antibody
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中文名稱：LMO4兔多克隆抗體
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貨號：CSB-PA286125
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA286125(LMO4 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
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其他：
產品詳情
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Uniprot No.：
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基因名：LMO4
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別名：Breast tumor autoantigen antibody; LIM domain only 4 antibody; LIM domain only protein 4 antibody; LIM domain transcription factor LMO 4 antibody; LIM domain transcription factor LMO4 antibody; LMO 4 antibody; LMO-4 antibody; LMO4 antibody; LMO4_HUMAN antibody; OTTHUMP00000011905 antibody; OTTHUMP00000011906 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Fusion protein of Human LMO4
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 IHC 1:20-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Probable transcriptional factor.
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基因功能參考文獻：
- Lmo4 participates in the regulation of lung epithelial cell proliferation but is not essential for tumor progression. PMID: 26048572
- LMO4 appears to form a hub in protein-protein interaction networks, linking numerous pathways within cells. PMID: 25310299
- Clim2, in a complex with LMO4, supports mammary stem cells by directly targeting the Fgfr2 promoter in basal cells to increase its expression PMID: 25079073
- Existence of a region in the lateral portion of the mammalian cochlea that is competent to make an organ of Corti is demonstrated in the absence of LMO4 function. PMID: 25057208
- Low LMO4 mRNA levels were associated with response to erlotinib in non-small-cell lung cancer. PMID: 23407556
- oncoprotein HBXIP is able to activate the transcriptional coregulatory protein LMO4 through transcription factor Sp1 in promotion of proliferation of breast cancer cells. PMID: 23291272
- Data suggest that overexpression of LMO4 may disrupt some of the normal tumour suppressor activities of CtIP, thereby contributing to breast cancer progression. PMID: 23353824
- the association of high levels of LMO4 with aggressive neuroblastomas is dependent on LMO4 regulation of cadherin expression and hence, tumor invasiveness PMID: 23407937
- LMO4 is a direct target of p53 and inhibits p53-mediated proliferative inhibition of breast cancer cells through interacting p53 PMID: 22906635
- LMO4 is over-expressed in highly invasive rhabdomyosarcoma, alveolar cells PMID: 21271214
- LMO4 expression in squamous cell carcinoma of the anterior tongue PMID: 21362019
- data indicate that LMO4 has similar cellular effects in normal mammary epithelial cells and breast cancer cells, and also provide direct evidence for the idea that normal development and carcinogenesis share conserved molecular mechanisms PMID: 20526802
- LMO4 protects neurons from ischemic brain injury, in part through its requirement as an essential cofactor of PPAR gamma PMID: 19020036
- These findings reveal a novel complex between BRCA1, LMO4, and CtIP and indicate a role for LMO4 as a repressor of BRCA1 activity in breast tissue. PMID: 11751867
- 1H, 15N and 13C assignments of FLIN4, an intramolecular LMO4:ldb1 complex PMID: 12153047
- Lmo4 RNA overexpression interferes with neuritic outgrowth,anti-sense Lmo4 RNA expression favors neuritogenesis in SH-SY5Y cells. Changes in Lmo4 RNA expression levels might alter the rate of neuritic outgrowth in the developing and adult nervous system. PMID: 12877980
- LMO4 interaction modulates the interleukin-6 receptor subunit glycoprotein 130 complex and its signaling PMID: 15677447
- LMO4 is consistently more highly expressed in the embryonic right perisylvian cerebral cortex than in the left PMID: 15894532
- LMO4 in breast epithelium contributes directly to breast neoplasia by altering the rate of cellular proliferation and promoting cell invasion. PMID: 15897450
- Artificial intramolecular cyclic protein complex between two interacting proteins: the largely unstable LIM-only protein 4 (LMO4) and an unstructured domain of LIM domain binding protein 1 (ldb1). PMID: 17001033
- In this study, patients whose tumours exhibited high LMO4 expression had a significant survival advantage following operative resection PMID: 18231110
- Results suggested that LMO4 is overexpressed at late stages in carcinogenesis of pancreatic cancer. PMID: 19099607
- Lmo4 expression coincides with the timing of the development of the somatosensory barrel field. PMID: 19111533
- LMO4 is a novel cell cycle regulator with a key role in mediating ErbB2-induced proliferation, a hallmark of ErbB2-positive disease. PMID: 19648968
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