KIAA0391 Antibody
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中文名稱：KIAA0391兔多克隆抗體
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貨號：CSB-PA012187ESR1HU
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規(guī)格：￥440
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圖片：
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Western blot
All lanes: KIAA0391 antibody at 1.06µg/ml
Lane 1: LO2 whole cell lysate
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 68, 66, 25, 57 kDa
Observed band size: 68 kDa -
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA012187ESR1HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA012187ESR1HU at dilution of 1:100
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) KIAA0391 Polyclonal antibody
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Uniprot No.：
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基因名：KIAA0391
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別名：Kiaa0391 antibody; KIAA0391 gene antibody; Mitochondrial ribonuclease P protein 3 antibody; Mitochondrial RNase P protein 3 antibody; Mitochondrial RNase P subunit 3 antibody; MRPP3 antibody; MRRP3_HUMAN antibody; PRORP antibody; Proteinaceous RNase P antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Mitochondrial ribonuclease P catalytic subunit protein (314-583AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：Catalytic ribonuclease component of mitochondrial ribonuclease P, a complex composed of TRMT10C/MRPP1, HSD17B10/MRPP2 and PRORP/MRPP3, which cleaves tRNA molecules in their 5'-ends. The presence of TRMT10C/MRPP1, HSD17B10/MRPP2 is required to catalyze tRNA molecules in their 5'-ends.
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基因功能參考文獻：
- This study presents the crystal structure of human MRPP3, which features a remarkably distorted and hence non-productive active site that authors propose will switch to a fully productive state only upon association with MRPP1, MRPP2 and pre-tRNA substrate. PMID: 25953853
- using a genome-wide association study, found that posttranscriptional modification of functionally important sites in mitochondrial transfer RNAs (tRNAs) is under strong genetic control, largely driven by a missense mutation in MRPP3 PMID: 24763589
- Inhibition of mitochondrial RNase P by beta-amyloid is an unspecific effect and is not mediated by beta-amyloid interaction with SDR5C1. PMID: 23755257
- Haplotypes in KIAA0391 and PSMA6 genes is a genetic link for myocardial infarction and coronary artery disease. PMID: 19624571
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亞細胞定位：Mitochondrion.
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蛋白家族：PPR family, P subfamily
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數(shù)據(jù)庫鏈接：
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