INCA1 Antibody

中文名稱：

INCA1兔多克隆抗體
貨號(hào)：

CSB-PA605764LA01HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA605764LA01HU at dilution of 1:100
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) INCA1 Polyclonal antibody
Uniprot No.：

Q0VD86
基因名：

INCA1
別名：

HSD45 antibody; Inca1 antibody; INCA1_HUMAN antibody; Inhibitor of CDK cyclin A1 interacting protein 1 antibody; Inhibitor of CDK interacting with cyclin A1 antibody; MGC148150 antibody; MGC148151 antibody; Protein INCA1 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Protein INCA1 protein (1-236AA)
免疫原種屬：

Homo sapiens (Human)

標(biāo)記方式：

Non-conjugated

本頁面中的產(chǎn)品，INCA1 Antibody (CSB-PA605764LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于INCA1 Antibody，我們還提供其他標(biāo)記。見下表：

標(biāo)記方式	貨號(hào)	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA605764LB01HU	INCA1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA605764LC01HU	INCA1 Antibody, FITC conjugated
Biotin	CSB-PA605764LD01HU	INCA1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Binds to CDK2-bound cyclins and inhibits the kinase activity of CDK2; binding to cyclins is critical for its function as CDK inhibitor. Inhibits cell growth and cell proliferation and may play a role in cell cycle control. Required for ING5-mediated regulation of S-phase progression, enhancement of Fas-induced apoptosis and inhibition of cell growth.
基因功能參考文獻(xiàn)：
1. Inhibitor of cyclin-dependent kinase (CDK) interacting with cyclin A1 (INCA1) regulates proliferation and is repressed by oncogenic signaling PMID: 21540187
2. Results indicate that ING5 is a growth suppressor with suppressed expression in AML whose functions depend on its interaction with INCA1. PMID: 21750715
亞細(xì)胞定位：

Nucleus. Cytoplasm.
蛋白家族：

INCA family
組織特異性：

Detected in testis, and at lower levels in ovary. Detected at very low levels in testis tumors. Down-regulated in bone marrow cells in acute myeloid and lymphoid leukemia patients as compared with normal bone marrow cells.
數(shù)據(jù)庫鏈接：

HGNC: 32224

OMIM: 617374

KEGG: hsa:388324

STRING: 9606.ENSP00000380041

UniGene: Hs.658926

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