HNRNPM Antibody
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中文名稱：HNRNPM兔多克隆抗體
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貨號：CSB-PA010613ESR2HU
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規格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA010613ESR2HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA010613ESR2HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) HNRNPM Polyclonal antibody
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Uniprot No.：
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基因名：HNRNPM
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別名：CEA receptor antibody; CEAR antibody; Heterogeneous nuclear ribonucleoprotein M antibody; Heterogenous nuclear ribonucleoprotein M4 antibody; hnRNA binding protein M4 antibody; hnRNP M antibody; Hnrnpm antibody; HNRNPM4 antibody; HNRPM antibody; HNRPM_HUMAN antibody; HNRPM4 antibody; HTGR1 antibody; M3 antibody; M4 antibody; M4 protein antibody; N-acetylglucosamine receptor 1 antibody; NAGR1 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Heterogeneous nuclear ribonucleoprotein M protein (491-730AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.
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基因功能參考文獻：
- Overexpression of hnRNPM promotes breast cancer aggressiveness by regulating the level of CD44s and indicates a poor prognosis. PMID: 28393427
- Data suggest that both heterogeneous nuclear ribonucleoprotein type M (HNRPM) and solute carrier 1A5 (SLC1A5) have role in the pathogenesis of ovarian cancer. PMID: 28609484
- p54nrb and hnRNPM knockdown silences the FGF1 promoter-dependent accumulation of mRNA during myoblast differentiation. PMID: 26332123
- Results suggest that glyceraldehyde-modified hnRNPM alters gene expression in nonalcoholic fatty liver disease. PMID: 25684943
- The authors propose that cleavage of and subverting the function of hnRNPM by 3C protease is a general strategy utilized by picornaviruses to facilitate viral infection. PMID: 25926642
- our data suggest that TAF15 and TLS/FUS operate within similar but not identical hnRNP M-TET protein complexes to influence the transcriptional or post-transcriptional output of a particular cell type. PMID: 24474660
- findings demonstrate a novel molecular mechanism through which tumor metastasis is endowed by the hnRNPM-mediated splicing program. PMID: 24840202
- Our results provide a clue that hnRNP M is a potential therapeutic target for Spinal muscular atrophy PMID: 24533984
- The present data demonstrate that the upregulation of HnRNP M is involved in human colorectal epithelial carcinogenesis and may serve as a carcinoma biomarker for colorectal cancer. PMID: 24381081
- Mechanistic control of carcinoembryonic antigen-related cell adhesion molecule-1 (CEACAM1) splice isoforms by the heterogeneous nuclear ribonuclear proteins hnRNP L, hnRNP A1, and hnRNP M. PMID: 21398516
- A central region in hnRNP-M is required for interaction with CDC5L/PLRG1. PMID: 20467437
- PSF (polypyrimidine tract-binding protein-associated splicing factor) and p54(nrb), two highly related proteins involved in transcription and RNA processing, are identified as new binding partners of hnRNP M. PMID: 19874820
- mitochondrial ribosomal protein S12 3'-UTR interacts specifically with TRAP1 (tumor necrosis factor receptor-associated protein1), hnRNPM4 (heterogeneous nuclear ribonucleoprotein M4), Hsp70 and Hsp60 (heat shock proteins 70 and 60), and alpha-tubulin PMID: 18790094
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亞細胞定位：Nucleus, nucleolus.
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數據庫鏈接：
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