GUF1 Antibody
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中文名稱：GUF1兔多克隆抗體
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貨號：CSB-PA040226
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規格：￥1090
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其他：
產品詳情
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Uniprot No.：
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基因名：GUF1
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別名：GUF1 antibody; Translation factor GUF1 antibody; mitochondrial antibody; EC 3.6.5.- antibody; Elongation factor 4 homolog antibody; EF-4 antibody; GTPase GUF1 antibody; Ribosomal back-translocase antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Synthesized peptide derived from the Internal region of Human GUF1.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：IHC, ELISA
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推薦稀釋比：
Application Recommended Dilution IHC 1:100-1:300 ELISA 1:20000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
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基因功能參考文獻：
- Homozygous variant in the GUF1 gene identified in the three siblings with West syndrome. PMID: 26486472
- The structure provides insights into the tRNA-remodeling function of EF-4 on the ribosome and suggests that the displacement of the CCA-end of the A-site tRNA away from the peptidyl transferase center (PTC) is functionally significant. PMID: 27092003
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相關疾病：Epileptic encephalopathy, early infantile, 40 (EIEE40)
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亞細胞定位：Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
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蛋白家族：TRAFAC class translation factor GTPase superfamily, Classic translation factor GTPase family, LepA subfamily
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數據庫鏈接：
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