GCNT2 Antibody
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中文名稱：GCNT2兔多克隆抗體
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貨號：CSB-PA009328LA01HU
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規(guī)格：￥440
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) GCNT2 Polyclonal antibody
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Uniprot No.：
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基因名：GCNT2
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別名：GCNT2 antibody; GCNT5 antibody; II antibody; NACGT1 antibody; N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase antibody; N-acetylglucosaminyltransferase antibody; EC 2.4.1.150 antibody; I-branching enzyme antibody; IGNT antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase protein (201-402AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產(chǎn)品，GCNT2 Antibody (CSB-PA009328LA01HU)，的標記方式是Non-conjugated。對于GCNT2 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關產(chǎn)品
靶點詳情
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功能：Branching enzyme that converts linear into branched poly-N-acetyllactosaminoglycans. Introduces the blood group I antigen during embryonic development. It is closely associated with the development and maturation of erythroid cells.; Determines the expression of the blood group I antigen in erythrocytes.
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基因功能參考文獻：
- miR-199a/b-5p regulates GCNT2 and I antigen expression in colon cancer cells undergoing EMT PMID: 28542779
- This study reports a novel insertion/deletion mutation at the GCNT2 locus that is responsible for congenital cataracts in a large consanguineous family. PMID: 27936067
- GCNT2 expression is closely associated with invasive potential of prostate cancer. PMID: 26678556
- Hypomethylation of the GCNT2 variant 2 reflected lymph node metastasis of colorectal cancer in the tumor and normal tissues. PMID: 25750292
- An Alu repeat-mediated genomic GCNT2 deletion underlies congenital cataracts and adult i blood group PMID: 21761136
- Results show involvement of GCNT2 in EMT and TGF-beta signaling, and further glycosylation modification of E-cadherin by GCNT2, are the underlying integrative mechanisms for breast cancer metastasis. PMID: 21750175
- In the family with the "ii" blood group a novel GCNT2 mutation was found in the cataract patients. PMID: 21541272
- The I carbohydrate antigen interacts simultaneously with the entire hydrophobic patch in framework region 1 and with the outside surface of Ig heavy chain complementarity-determining region 3, leaving most of the site available for binding other antigens. PMID: 12244172
- A nonsense mutation in the GCNT2 gene isoforms is associated with autosomal recessive congenital cataract in four distantly related Arab families from Israel. PMID: 15161861
- role of C/EBPalpha in the induction of the IGnTC gene as well as in I antigen expression PMID: 17855628
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相關疾病：Cataract 13, with adult i phenotype (CTRCT13)
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亞細胞定位：Golgi apparatus membrane; Single-pass type II membrane protein.
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蛋白家族：Glycosyltransferase 14 family
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組織特異性：[Isoform B]: Expressed in lens epithelium cells.; [Isoform C]: Expressed in reticulocytes.
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數(shù)據(jù)庫鏈接：
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