FCRL6 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) FCRL6 Polyclonal antibody
Uniprot No.：

Q6DN72
基因名：

FCRL6
別名：

Fc receptor homolog 6 antibody; Fc receptor-like 6 antibody; Fc receptor-like protein 6 antibody; Fc receptor-like protein 7 antibody; FcR-like protein 6 antibody; FcRH6 antibody; FcRL6 antibody; FCRL6_HUMAN antibody; FLJ16056 antibody; IFGP6 antibody; IgSF type I transmembrane receptor antibody; leukocyte receptor antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Fc receptor-like protein 6 protein (20-307AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor.
基因功能參考文獻：
1. Human FCRL6 receptor, selectively expressed by cytotoxic T and natural killer (NK) cells, directly binds the major histocompatibility complex (MHC) class II molecule HLA-DR. PMID: 20519654
2. FCRL6 is a distinct indicator of cytotoxic effector lymphocytes that is upregulated in diseases characterized by chronic immune stimulation. PMID: 18991291
亞細胞定位：

Cell membrane; Single-pass type I membrane protein.
組織特異性：

Expressed by cytolytic cells including NK cells, effector and effector-memory CD8(+) T-cells, and a subset of NKT cells (at protein level). Also expressed in gamma delta T cells and in a rare subset of effector CD4(+) T-cells (at protein level). Expressed
數據庫鏈接：

HGNC: 31910

OMIM: 613562

KEGG: hsa:343413

UniGene: Hs.196955

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