EGR3 Antibody, FITC conjugated
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中文名稱：EGR3兔多克隆抗體, FITC偶聯
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貨號：CSB-PA007486LC01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) EGR3 Polyclonal antibody
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Uniprot No.：
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基因名：EGR3
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別名：EGR3 antibody; PILOTEarly growth response protein 3 antibody; EGR-3 antibody; Zinc finger protein pilot antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Early growth response protein 3 protein (201-281AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Probable transcription factor involved in muscle spindle development.
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基因功能參考文獻：
- KSRP decreased EGR3 mRNA stability in an ARE-independent manner. PMID: 28847731
- miR-718 acts as a tumor suppressive microRNA in hepatocellular carcinoma via regulating the expression of EGR3, which may provide a new diagnostic marker and treatment target for HCC PMID: 28070994
- EGR3 contributes to cell growth inhibition via upregulation of FasL in Hepatocellular carcinoma. PMID: 28098878
- These findings support previously reported associations between EGR3 and schizophrenia. PMID: 26474411
- EGR3 promotes excessive production of IL6 and IL8 observed during the progression of prostate cancer. PMID: 25633035
- Data shows association of Egr3 genetic polymorphisms and coronary artery disease in the Uygur and Han of China PMID: 24886494
- Genetic variation in EGR3 may affect prefrontal function through neurodevelopment PMID: 23962955
- These results provide the first evidence that Egr-3, is up-regulated in scleroderma and is necessary and sufficient for profibrotic responses. PMID: 23906810
- Decreased EGR3 expression might play a critical role in the differentiation, proliferation, metastasis and progression of gastric cancer cells. PMID: 23460371
- These data suggest that type I IFN stimulation induces a rapid recruitment of a repressive Egr3/Nab1 complex that silences transcription from the ifngr1 promoter. PMID: 23935197
- Our results suggest that Egr-3 is a transcription factor associated with TGF-beta1 expression and in vivo regulatory activity PMID: 23904169
- Egr3 mRNA expression reveals that Egr3 mRNA expression is increased in tumor cells of non-relapsed samples compared to normal prostate cells, but is significantly lower in relapsed samples compared to non-relapse. PMID: 23342084
- EGR3, a gene that translates environmental stimuli into long-term changes in the brain, may be associated with risk for child bipolar disorder 1. PMID: 22370066
- Study supports the association of EGR3 with schizophrenia in Han Chinese sample. PMID: 22276163
- EGR3 gene may play an important role in schizophrenia susceptibility PMID: 22425949
- EGR3 bound to the TREM-1 promoter. PMID: 21421043
- This study demoistrated that ERG3 are not genetic risk factors for schizophrenia in japanese. PMID: 20537399
- SNP rs35201266 in intron 1 of the EGR3 gene showed a significant association with schizophrenia PMID: 20687139
- Egr-3 is a critical determinant of VEGF signaling in activated endothelial cells PMID: 19965691
- Vascularendothelial growth factor induces expression of NR4A nuclear receptors and Egr3 via KDR and KDR-mediated signaling mechanisms. PMID: 14525795
- data suggest that Egr3 is a target for the estrogen receptor alpha PMID: 15171706
- These findings support the previous genetic association of altered calcineurin signaling with schizophrenia pathogenesis and identify EGR3 as a compelling susceptibility gene. PMID: 17360599
- findings indicate that Egr3 has an essential downstream role in VEGF-mediated endothelial functions leading to angiogenesis and may have particular relevance for adult angiogenic processes involved in vascular repair and neovascular disease PMID: 18059339
- Enforced expression of Egr3 transgene, from the CD2 antigen promoter, facilitates development of RAG2-deficient double-negative (DN) stage 3 thymocytes to the DN4 stage and subsequently to the double-positive stage of development. PMID: 19124717
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亞細胞定位：Nucleus.
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蛋白家族：EGR C2H2-type zinc-finger protein family
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數據庫鏈接：
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