EEF1E1 Antibody
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中文名稱：EEF1E1兔多克隆抗體
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貨號(hào)：CSB-PA007432GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：EEF1E1
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別名：AIMP 3 antibody; AIMP3 antibody; Aminoacyl tRNA synthetase complex interacting multifunctional protein 3 antibody; Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3 antibody; ARS interacting multifunctional protein 3 antibody; EEF1E1 antibody; Elongation factor p18 antibody; Eukaryotic translation elongation factor 1 epsilon 1 antibody; Eukaryotic translation elongation factor 1 epsilon-1 antibody; Homolog of rat elongation factor p18 antibody; MCA3_HUMAN antibody; Multisynthase complex auxiliary component p18 antibody; Multisynthetase complex auxiliary component p18 antibody; p18 antibody; p18 component of aminoacyl tRNA synthetase complex antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human EEF1E1
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB,IHC
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Positive modulator of ATM response to DNA damage.
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基因功能參考文獻(xiàn)：
- LmnA binds AIMP3 via its extreme C-terminus. Together these findings provide a structural insight for understanding the interaction between AIMP3 and LmnA in AIMP3 degradation. PMID: 28797100
- AIMP3 was shown to be involved in the cellular aging of human mesenchymal stem cells. PMID: 25465621
- Identification of EEf1E1 and OBFC2B as novel BRCA1-partner genes in the DNA double-strand break repair pathway. PMID: 24104880
- AIMP3 stabilizes and protects methionyl-tRNA synthetase and eIF2gamma through the binding interactions. PMID: 23306449
- AIMP3 is a critical mediator of Met-tRNA(i)(Met) transfer from methionyl-tRNA synthetase to eIF2 complex for the accurate and efficient translation initiation PMID: 22867704
- Data show that aminoacyl-tRNA synthetase-interacting multifunctional protein-3 (AIMP3)/p18 is released from aminoacyl-tRNA synthetase-interacting multifunctional protein-3 (AIMP3) by UV irradiation-induced stress. PMID: 22106287
- Decreased expression of AIMP3 in gastric and colorectal cancer tissues suggests that down-regulation of this protein may be related to inactivation of the tumor suppressor functions of AIMP proteins and might play a role in the development of GC and CRC. PMID: 21789020
- p18 is a haploinsufficient tumor suppressor and a key factor for ATM/ATR-mediated p53 activation. PMID: 15680327
- analysis of the three-dimensional structure and residues of the novel tumor suppressor AIMP3/p18 required for the interaction with PMID: 18343821
- No EEF1E1 mutations were detected in human cancer specimens. PMID: 19024604
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亞細(xì)胞定位：Cytoplasm. Cytoplasm, cytosol. Nucleus. Note=Cytoplasmic under growth arrest conditions. Translocated into the nucleus when growth resumes (S phase) and following DNA damage.
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組織特異性：Down-regulated in various cancer tissues.
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數(shù)據(jù)庫鏈接：
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