DUSP13 Antibody

說明書

中文名稱：

DUSP13兔多克隆抗體
貨號：

CSB-PA693441
規格：

￥1100
圖片：
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA693441(DUSP13 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA693441(DUSP13 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)
其他：

產品詳情

Uniprot No.：

Q9UII6
基因名：

DUSP13
別名：

DUSP13 antibody; DUSP13B antibody; TMDPDual specificity protein phosphatase 13 isoform B antibody; DUSP13B antibody; EC 3.1.3.16 antibody; EC 3.1.3.48 antibody; Dual specificity phosphatase SKRP4 antibody; Testis- and skeletal-muscle-specific DSP antibody
宿主：

Rabbit
反應種屬：

Human,Mouse
免疫原：

Fusion protein of Human DUSP13
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

Antigen affinity purification
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
產品提供形式：

Liquid
應用范圍：

ELISA,IHC

推薦稀釋比：

Application	Recommended Dilution
ELISA	1:2000-1:5000
IHC	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Dual specificity phosphatase that dephosphorylates MAPK8/JNK and MAPK14/p38, but not MAPK1/ERK2, in vitro. Exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues, with similar specific activities in vitro.
基因功能參考文獻：
1. data suggest an important role for DUSP13B in protection from external stress during spermatogenesis PMID: 21360282
2. identified a gene on chromosome 10q22.2 using alternative ORFs to encode two distinct DSPs: the testis and skeletal muscle-specific TMDP and a novel muscle-restricted DSP(MDSP) PMID: 15252030
3. Here, we report the crystal structure of human TMDP at a resolution of 2.4 A. In spite of high sequence similarity with other DSPs, the crystal structure of TMDP shows distinct structural motifs and surface propertie PMID: 17044055
蛋白家族：

Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
組織特異性：

Highly expressed in the testis (at protein level). Also found in the skeletal muscle.
數據庫鏈接：

HGNC: 19681

OMIM: 613191

STRING: 9606.ENSP00000452702

UniGene: Hs.178170

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