DUSP13 Antibody, HRP conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) DUSP13 Polyclonal antibody
Uniprot No.：

Q9UII6
基因名：

DUSP13
別名：

DUSP13 antibody; DUSP13B antibody; TMDPDual specificity protein phosphatase 13 isoform B antibody; DUSP13B antibody; EC 3.1.3.16 antibody; EC 3.1.3.48 antibody; Dual specificity phosphatase SKRP4 antibody; Testis- and skeletal-muscle-specific DSP antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Dual specificity protein phosphatase 13 isoform B protein (1-198AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Dual specificity phosphatase that dephosphorylates MAPK8/JNK and MAPK14/p38, but not MAPK1/ERK2, in vitro. Exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues, with similar specific activities in vitro.
基因功能參考文獻：
1. data suggest an important role for DUSP13B in protection from external stress during spermatogenesis PMID: 21360282
2. identified a gene on chromosome 10q22.2 using alternative ORFs to encode two distinct DSPs: the testis and skeletal muscle-specific TMDP and a novel muscle-restricted DSP(MDSP) PMID: 15252030
3. Here, we report the crystal structure of human TMDP at a resolution of 2.4 A. In spite of high sequence similarity with other DSPs, the crystal structure of TMDP shows distinct structural motifs and surface propertie PMID: 17044055
蛋白家族：

Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
組織特異性：

Highly expressed in the testis (at protein level). Also found in the skeletal muscle.
數據庫鏈接：

HGNC: 19681

OMIM: 613191

STRING: 9606.ENSP00000452702

UniGene: Hs.178170

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