DHODH Antibody
-
中文名稱：DHODH兔多克隆抗體
-
貨號(hào)：CSB-PA007799
-
規(guī)格：￥1090
-
圖片：
-
Western Blot analysis of Jurkat cells using DHODH Polyclonal Antibody
-
-
其他：
產(chǎn)品詳情
-
Uniprot No.：
-
基因名：DHODH
-
別名：DHOdehase antibody; Dhodh antibody; Dihydroorotate dehydrogenase (quinone) antibody; Dihydroorotate dehydrogenase antibody; Dihydroorotate dehydrogenase mitochondrial antibody; Dihydroorotate oxidase antibody; Human complement of yeast URA1 antibody; mitochondrial antibody; POADS antibody; PYRD_HUMAN antibody; URA1 antibody
-
宿主：Rabbit
-
反應(yīng)種屬：Human
-
免疫原：Synthesized peptide derived from the Internal region of Human DHODH.
-
免疫原種屬：Homo sapiens (Human)
-
標(biāo)記方式：Non-conjugated
-
抗體亞型：IgG
-
純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
-
產(chǎn)品提供形式：Liquid
-
應(yīng)用范圍：WB, IHC, ELISA
-
推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:40000 -
Protocols：
-
儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
-
功能：Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
-
基因功能參考文獻(xiàn)：
- This case with grossly raised plasma DHO represents the first biochemical confirmation of functional DHODH deficiency. DHO was also easily detectable in dried plasma and blood spots. PMID: 27370710
- This is the first study to report on conformational changes of the HsDHODH N-terminal microdomain through a combination of CD and DEER spectroscopic techniques PMID: 26086954
- Considering that pyrimidine deficiency alone does not induce craniofacial dysmorphism, the DHODH mutations may contribute to the Miller syndrome in part through somehow altered mitochondrial function. PMID: 23216091
- Carriage of a six-marker DHODH haplotype was associated with a reduced treatment response (p = 0.008). PMID: 22966891
- The G202A and R346W mutation causes deficient protein stability, and the R135C mutation impairs the substrate-induced enzymatic activity, suggesting that impairment of DHODH activity is linked to the Miller syndrome phenotype. PMID: 22967083
- biallelic DHODH mutations in four unrelated families with typical clinical features of Miller syndrome. PMID: 22692683
- DHODH inhibition led to a marked decrease in melanoma growth both in vitro and in xenograft studies PMID: 21430780
- DHODH recessively causes Miller syndrome. PMID: 20220176
- required for N-(4-hydroxyphenyl)retinamide-induced reactive oxygen species production and apoptosis of cancer epithelial cells PMID: 20399851
- Data confirmed the presence of DHODH mutations in families with Miller syndrome. PMID: 19915526
- biophysical analysis of hydrogen bonding pathways in human dihydroorotate dehydrogenase PMID: 17004840
- Data provide new insights into the dynamic features of the DHODH reaction and suggest new approaches to the design of inhibitors against DHODH. PMID: 18672895
- DHODH polymorphism may be associated with incireased remiaaion in leflunomide treatment in rheumatoid arthritis patients. PMID: 19207032
- we report a new association of DHODH A40C polymorphism with leflunomide toxicity in patients with Rheumatoid Arthritis. PMID: 19605743
顯示更多
收起更多
-
相關(guān)疾?。?/div>Postaxial acrofacial dysostosis (POADS)亞細(xì)胞定位：Mitochondrion inner membrane; Single-pass membrane protein.蛋白家族：Dihydroorotate dehydrogenase family, Type 2 subfamily數(shù)據(jù)庫(kù)鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
