CTSZ Antibody, Biotin conjugated
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中文名稱：CTSZ兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA006206LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) CTSZ Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：Carboxypeptidase LB antibody; Cathepsin B2 antibody; Cathepsin IV antibody; Cathepsin P antibody; Cathepsin X antibody; Cathepsin X precursor antibody; Cathepsin Y antibody; Cathepsin Z antibody; Cathepsin Z precursor antibody; Cathepsin Z1 antibody; CathepsinP antibody; CathepsinX antibody; CathepsinZ antibody; CATZ_HUMAN antibody; CTSX antibody; CTSZ antibody; Cysteine type carboxypeptidase antibody; FLJ17088 antibody; Lysosomal carboxypeptidase B antibody; Preprocathepsin P antibody; PreprocathepsinP antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Cathepsin Z protein (127-287AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity. Capable of producing kinin potentiating peptides.
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基因功能參考文獻：
- Down-regulation of RPLP0 resulted in G1 arrest of gastric cancer cells, whereas knockdown of Cathepsin X led to G1 arrest and apoptosis PMID: 25433997
- Cathepsin X (CTSX) is involved in early tumorigenesis and in the stabilization of tumor cell formation in colorectal cancer. PMID: 25442015
- The significant association of cathepsin X with survival in a group of patients who received no chemotherapy and the absence of this association in the group who received chemotherapy, suggest the possible predictive value for response to chemotherapy. PMID: 24725597
- Suggest CTSZ rs34069356 polymorphism is not associated with pulmonary tuberculosis in a sample Iranian population. PMID: 23827504
- We show that sequential cleavage of C-terminal amino acids from the beta(2) cytoplasmic tail of LFA-1, by CatX, enhances binding of the adaptor protein talin to LFA-1 and triggers formation of the latter's high-affinity form PMID: 21454358
- cathepsin Z contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma PMID: 21966391
- cathepsin X deficiency leads to accelerated cellular senescence and consequently to diminished cellular proliferation and migration/invasion implying a potential role of cathepsin X in bypassing cellular senescence. PMID: 21616554
- Polymorphisms in MC3R promoter and CTSZ 3'UTR are associated with tuberculosis susceptibility. PMID: 21368909
- associated with tuberculosis in a Ugandan household contact study PMID: 21354459
- Cysteine proteases bleomycin hydrolase and cathepsin Z mediate N-terminal proteolysis and toxicity of mutant huntingtin. PMID: 21310951
- These results show that cathepsin P, in contrast to other mammalian cathepsins, has a restricted catalytic specificity. PMID: 15680921
- the extracellular function of cathepsin X may include binding to integrins thereby modulating the attachment of migrating cells to ECM components [Cathepsin X] PMID: 17065156
- unlikely that CTSZ gene plays a major role in tuberculosis susceptibility in African populations PMID: 18420963
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亞細胞定位：Lysosome.
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蛋白家族：Peptidase C1 family
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組織特異性：Widely expressed.
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數據庫鏈接：
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