CNOT4 Antibody
-
中文名稱：CNOT4兔多克隆抗體
-
貨號：CSB-PA005667GA01HU
-
規(guī)格：￥3,900
-
其他：
產(chǎn)品詳情
-
Uniprot No.：
-
基因名：CNOT4
-
別名：CCR4 NOT transcription complex subunit 4 antibody; CCR4-associated factor 4 antibody; CCR4-NOT transcription complex subunit 4 antibody; CLONE243 antibody; CNOT 4 antibody; Cnot4 antibody; CNOT4_HUMAN antibody; E3 ubiquitin-protein ligase CNOT4 antibody; NOT 4 antibody; NOT4 (negative regulator of transcription 4 yeast) homolog antibody; NOT4 antibody; NOT4H antibody; Potential transcriptional repressor NOT4Hp antibody
-
宿主：Rabbit
-
反應(yīng)種屬：Human,Mouse,Rat
-
免疫原：Human CNOT4
-
免疫原種屬：Homo sapiens (Human)
-
抗體亞型：IgG
-
純化方式：Antigen Affinity Purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
-
產(chǎn)品提供形式：Liquid
-
應(yīng)用范圍：ELISA,WB,IHC
-
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
-
功能：Has E3 ubiquitin ligase activity, promoting ubiquitination and degradation of target proteins. Involved in activation of the JAK/STAT pathway. Catalyzes ubiquitination of methylated RBM15. Plays a role in quality control of translation of mitochondrial outer membrane-localized mRNA. As part of the PINK1-regulated signaling, upon mitochondria damage, ubiquitinates ABCE1 and thereby recruits autophagy receptors to the mitochondrial outer membrane to initiate mitophagy.
-
基因功能參考文獻(xiàn)：
- These results indicate that CNOT4 is a ubiquitin ligase of influenza A virus nucleoprotein, and ubiquitination of the nucleoprotein plays a positive role in viral RNA replication. PMID: 28536288
- CNOT4 controls the degradation of chromatin-unbound PAF1 via the 26S proteasome. PMID: 25933433
- Single nucleotide polymorphism in CNOT4 gene is associated with osteosarcoma susceptibility. PMID: 25663449
- Data show that Not4/CNOT4 is a novel positive regulator of the JAK/STAT pathway in Drosophila and in humans. PMID: 22159038
- Data show that binding of the CNOT4 RING finger to the ubiquitin-conjugating enzyme (E2) UbcH5B is highly selective PMID: 15001359
- Data show that Ccr4-Not function in RNA splicing and nuclear export, and that CNOT4 binds CNOT1 in yeast two-hybrid assays. PMID: 19558367
顯示更多
收起更多
-
亞細(xì)胞定位：Cytoplasm. Nucleus.
-
數(shù)據(jù)庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
-
-
-
-
-
