CDON Antibody
-
中文名稱：CDON兔多克隆抗體
-
貨號：CSB-PA005100GA01HU
-
規(guī)格：￥3,900
-
其他：
產品詳情
-
Uniprot No.：
-
基因名：
-
別名：CDO antibody; Cdon antibody; CDON_HUMAN antibody; Cell adhesion molecule-related/down-regulated by oncogenes antibody
-
宿主：Rabbit
-
反應種屬：Human,Mouse,Rat
-
免疫原：Human CDON
-
免疫原種屬：Homo sapiens (Human)
-
抗體亞型：IgG
-
純化方式：Antigen Affinity purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
-
產品提供形式：Liquid
-
應用范圍：ELISA,WB
-
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells.
-
基因功能參考文獻：
- We identified a novel heterozygous nonsense CDON mutation in a case of Pituitary Stalk Interruption Syndrome who presented with neonatal hypoglycemia and cholestasis PMID: 26529631
- CDO is required for proliferation and survival of lung cancer cells via Hh signaling. PMID: 25369201
- These data support the view that cell-adhesion molecule-related/downregulated by oncogenes (CDON) acts as a tumor suppressor in neuroblastomas, and that CDON is tightly regulated by miRNAs. PMID: 25313246
- Single-nucleotide polymorphism in CDON is associated with biochemical recurrence in prostate cancer. PMID: 24740842
- Mutations in the CDON cause holoprosencephaly. (Review) PMID: 22326621
- We found that CDON is overexpressed in prostate cancer PMID: 21849809
- CDON must associate with both ligand and other hedgehog-receptor components, particularly PTCH1, for signaling to occur and disruption of the latter interactions is a mechanism of holoprosencephaly. PMID: 21802063
- Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner PMID: 20519495
- CDO and BOC play a role in differentiation of cells in the skeletal muscle lineage PMID: 12720294
- CDO and BOC forms complexes with specific cadherins that mediate some of the promyogenic effects of cell-cell contact. PMID: 12634428
- Targeted inactivation of Cdon in the mouse results in mild holoprosencephaly, suggesting a link to signaling pathways that control midline development such as the Sonic hedgehog pathway. PMID: 12620190
顯示更多
收起更多
-
相關疾病：Holoprosencephaly 11 (HPE11)
-
亞細胞定位：Cell membrane; Single-pass membrane protein.
-
數(shù)據(jù)庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
