CDC42EP2 Antibody
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中文名稱：CDC42EP2兔多克隆抗體
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貨號：CSB-PA006510
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規格：￥1090
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圖片：
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Western Blot analysis of K562 cells using Cdc42EP2 Polyclonal Antibody
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其他：
產品詳情
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Uniprot No.：
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基因名：CDC42EP2
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別名：Binder of Rho GTPases 1 antibody; BORG1 antibody; BORG1_HUMAN antibody; CDC42 effector protein (Rho GTPase binding) 2 antibody; Cdc42 effector protein 2 antibody; Cdc42ep2 antibody; CEP2 antibody; CRIB-containing BOGR1 protein antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Synthesized peptide derived from the N-terminal region of Human Cdc42EP2.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB, IHC, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:40000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.
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基因功能參考文獻：
- Studies indicate some of the functional and mechanistic roles of the binder of Rho GTPases Borg1-5 proteins (Cdc42EP1-5), including cytoskeletal remodelling and signalling. PMID: 27913681
- CDC42EP2 is upregulated in human PDLCs subjected to tensile stress related to mechano-induced cell cycle arrest. PMID: 20934684
- activations of Rac1 and Cdc42 are involved in the hypoxia-induced production of angiogenesis-promoting factors and tumor suppressors, and suggest that the Rho family GTPases Rac1 and Cdc42 may contribute to the hypoxia-mediated angiogenesis. PMID: 16395716
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亞細胞定位：Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.
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蛋白家族：BORG/CEP family
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組織特異性：Highly expressed in the heart. Weakly expressed in the pancreas and liver.
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數據庫鏈接：
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