CDC42EP2 Antibody
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中文名稱：CDC42EP2兔多克隆抗體
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貨號：CSB-PA546490
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規(guī)格：￥2024
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圖片：
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Western blot analysis of extracts from K562 cells, using BORG1 antibody.
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) CDC42EP2 Polyclonal antibody
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Uniprot No.：
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基因名：CDC42EP2
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Synthesized peptide derived from internal of Human BORG1.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:3000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.
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基因功能參考文獻(xiàn)：
- Studies indicate some of the functional and mechanistic roles of the binder of Rho GTPases Borg1-5 proteins (Cdc42EP1-5), including cytoskeletal remodelling and signalling. PMID: 27913681
- CDC42EP2 is upregulated in human PDLCs subjected to tensile stress related to mechano-induced cell cycle arrest. PMID: 20934684
- activations of Rac1 and Cdc42 are involved in the hypoxia-induced production of angiogenesis-promoting factors and tumor suppressors, and suggest that the Rho family GTPases Rac1 and Cdc42 may contribute to the hypoxia-mediated angiogenesis. PMID: 16395716
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亞細(xì)胞定位：Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.
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蛋白家族：BORG/CEP family
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組織特異性：Highly expressed in the heart. Weakly expressed in the pancreas and liver.
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數(shù)據(jù)庫鏈接：
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