BCLAF1 Antibody
-
中文名稱：BCLAF1兔多克隆抗體
-
貨號：CSB-PA559503
-
規(guī)格：￥2024
-
圖片：
-
Western blot analysis of extracts from 293 cells, Jurkat cells and A549 cells, using BCLAF1 antibody.
-
-
其他：
產(chǎn)品詳情
-
產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) BCLAF1 Polyclonal antibody
-
Uniprot No.：
-
基因名：
-
宿主：Rabbit
-
反應(yīng)種屬：Human
-
免疫原：Synthesized peptide derived from internal of Human BCLAF1.
-
免疫原種屬：Homo sapiens (Human)
-
克隆類型：Polyclonal
-
純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
濃度：It differs from different batches. Please contact us to confirm it.
-
產(chǎn)品提供形式：Liquid
-
應(yīng)用范圍：ELISA,WB
-
推薦稀釋比：
Application Recommended Dilution WB 1:500-1:3000 -
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點(diǎn)詳情
-
功能：Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
-
基因功能參考文獻(xiàn)：
- LTBR and BCLAF1 showed higher DNA methylation percentages in the marsupialized OKCs, but this difference did not affect gene expression (P > .05). PMID: 28864293
- Results indicate a role for the RNA processing factors THRAP3 and BCLAF1 in the regulation of the cellular DNA damage response (DDR) pathway. PMID: 29112714
- findings link treatment responsiveness to re-instatement of miR-194-5p/BCLAF1 balance PMID: 28216661
- SMYD3 physically interacts with the promoter of BCLAF1 and upregulates its expression by accumulating di- and trimethylation of H3K4 at the BCLAF1 locus. BCLAF1 depletion inhibits SMYD3-induced autophagy. PMID: 26676636
- The Bclaf1 can interact with the leucine zipper region of C/EBPbeta and cooperate with C/EBPbeta to upregulate IL-8. PMID: 26794446
- both cytoplasmic BCLAF1 expression and nuclear BCLAF1 expression are increased in post-neoadjuvant therapy rectal cancer, and that negative and weak nuclear BCLAF1 expression are independently associated with a poor prognosis PMID: 26183150
- SRSF10 is a key regulator of BCLAF1 pre-mRNA splicing and the maintenance of oncogenic features in human colon cancer cells PMID: 25091051
- BTF has functions distinct from TRAP150 in regulating the subcellular distribution of mRNAs in human cells. PMID: 23778535
- BCLAF1 co-localized with gammaH2AX foci in nuclei and stabilized the Ku70/DNA-PKcs complex therein, facilitating non-homologous end joining (NHEJ)-based DSB repair in surviving cells. PMID: 22833098
- In the absence of BclAF1 neutralization, viral gene expression and replication are inhibited. These data identify two temporally and mechanistically distinct functions used by human cytomegalovirus to down-regulate a cellular antiviral protein PMID: 22645331
- Sirt1 negatively regulates T cell activation via H3K56 deacetylation at the promoter region to inhibit transcription of Bclaf1 PMID: 21454709
- Findings indicate a role for BCLAF1 in post-transcriptional processes that impact mRNA metabolism. PMID: 20661537
- Two-dimensional differential in-gel electrophoresis (2D-DIGE) revealed the differential expression of 51 proteins in response to C16-ceramide. Cell death-promoting factor Btf was found to be implicated in the apoptotic signal triggered by ceramide. PMID: 19705920
- These results suggest that Btf localization is regulated by apoptotic signals, and that loss of emerin binding to Btf may be relevant to muscle wasting in Emery-Dreifuss muscular dystrophy. PMID: 15009215
- These findings provide evidence that activation of TP53 gene transcription by PKCdelta triggers TP53-dependent apoptosis in response to DNA damage. PMID: 17938203
顯示更多
收起更多
-
亞細(xì)胞定位：Cytoplasm. Nucleus. Nucleus speckle. Nucleus, nucleoplasm.
-
蛋白家族：BCLAF1/THRAP3 family
-
組織特異性：Ubiquitous.
-
數(shù)據(jù)庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
