BAIAP2L1 Antibody

說(shuō)明書(shū)

中文名稱：

BAIAP2L1兔多克隆抗體
貨號(hào)：

CSB-PA887045LA01HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA887045LA01HU at dilution of 1:100
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) BAIAP2L1 Polyclonal antibody
Uniprot No.：

Q9UHR4
基因名：

BAIAP2L1
別名：

BAI1 associated protein 2 like 1 antibody; BAI1 associated protein 2 like protein 1 antibody; BAI1-associated protein 2-like protein 1 antibody; Baiap2l1 antibody; BI2L1_HUMAN antibody; Brain specific angiogenesis inhibitor 1 associated protein 2 like protein 1 antibody; Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 antibody; FLJ42275 antibody; Insulin receptor tyrosine kinase substrate antibody; IRTKS antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 protein (1-190AA)
免疫原種屬：

Homo sapiens (Human)

標(biāo)記方式：

Non-conjugated

本頁(yè)面中的產(chǎn)品，BAIAP2L1 Antibody (CSB-PA887045LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于BAIAP2L1 Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

標(biāo)記方式	貨號(hào)	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA887045LB01HU	BAIAP2L1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA887045LC01HU	BAIAP2L1 Antibody, FITC conjugated
Biotin	CSB-PA887045LD01HU	BAIAP2L1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection.
基因功能參考文獻(xiàn)：
1. Rho family GTPases use the I-BAR proteins, IRSp53 (also known as BAIAP2), IRTKS and Pinkbar, as a central mechanism to modulate cell morphology. PMID: 27278019
2. IRTKS promoted serum-induced cell migration along with enhanced phosphorylation of mitogen activated kinases Erk1/2 and p38, and activation of small GTPases Rac1 and Cdc42. In addition, cells overexpressing IRTKS exhibited an increased polarity characterized by elongated cytoplasm and extensive lamellipodia at leading edges. PMID: 27693783
3. Upregulation of BAIAP2L1 is associated with ovarian cancer. PMID: 26222696
4. Lacking the Bin-Amphiphysin-Rvs (BAR) dimerization domain of BAIAP2L1. PMID: 25589496
5. IRTKS can interact with epidermal growth factor receptor (EGFR), results in the phosphorylation of extracellular signal-regulated kinase PMID: 23693078
6. Identification of a novel oncogenic FGFR3-BAIAP2L1 fusion protein in bladder cancer. PMID: 23175443
7. These data suggest that IRTKS is a novel regulator of p53, modulating low level of MDM2-mediated p53 ubiquitination in unstressed cells. PMID: 21887275
8. data suggest Src-stimulated IRTKS phosphorylation is essential for its function in cell motility PMID: 21840312
9. Results describe the NMR structure of insulin receptor tyrosine kinase substrate (IRTKS) SH3 domain in complex with a repeat from Escherichia coli-secreted protein F-like protein encoded on prophage U (EspF(U)). PMID: 21098279
10. Study characterised IRTKS, which has widespread tissue distribution, is a substrate for the insulin receptor and binds Rac, and expression of IRTKS induces clusters of short actin bundles rather than filopodia-like protrusions. PMID: 17430976
11. Screening of the mammalian SH3 proteome for the ability to bind EspF(U) identified the SH3 domain of insulin receptor tyrosine kinase substrate (IRTKS), a factor known to regulate the cytoskeleton. PMID: 19366662
顯示更多

收起更多
亞細(xì)胞定位：

Cytoplasm, cytoskeleton. Note=Recruited to actin pedestals that are formed upon infection by bacteria at bacterial attachment sites.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 21649

OMIM: 611877

KEGG: hsa:55971

STRING: 9606.ENSP00000005260

UniGene: Hs.656063

Most popular with customers

YWHAG Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
YWHAB Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC, IF, FC

Species Reactivity: Human, Mouse, Rat
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
XRCC5 Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC, IF

Species Reactivity: Human
XPNPEP1 Recombinant Monoclonal Antibody

Applications: ELISA, IHC, FC

Species Reactivity: Human
XDH Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
WT1 Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
WFDC2 Recombinant Monoclonal Antibody

Applications: ELISA, WB, FC

Species Reactivity: Human