AP1M1 Antibody
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中文名稱：AP1M1兔多克隆抗體
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貨號：CSB-PA001864GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：AP1M1
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別名：Adaptor protein complex AP-1 mu-1 subunit antibody; Adaptor-related protein complex 1 mu-1 subunit antibody; AP-1 complex subunit mu-1 antibody; AP-mu chain family member mu1A antibody; Ap1m1 antibody; AP1M1_HUMAN antibody; AP47 antibody; CLAPM2 antibody; Clathrin adaptor protein AP47 antibody; Clathrin assembly protein complex 1 medium chain 1 antibody; Clathrin assembly protein complex 1 medium chain antibody; Clathrin assembly protein complex AP1 mu subunit antibody; Clathrin coat assembly protein AP47 antibody; Clathrin coat-associated protein AP47 antibody; CLTNM antibody; Golgi adaptor AP 1 47 kDa protein antibody; Golgi adaptor HA1/AP1 adaptin mu-1 subunit antibody; HA1 47 kDa subunit antibody; MU 1A antibody; Mu-adaptin 1 antibody; Mu1A-adaptin antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human AP1M1
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
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基因功能參考文獻：
- found 31 ORF9p interaction partners, among which was AP1M1, the mu subunit of the adaptor protein complex 1 (AP-1). AP-1 is a heterotetramer involved in intracellular vesicle-mediated transport and regulates the shuttling of cargo proteins between endosomes and the trans-Golgi network via clathrin-coated vesicles. PMID: 29793951
- Acidic clusters act as sorting signals for packaging cargo into clathrin-coated vesicles (CCVs), and also facilitate down-regulation of MHC-I by HIV-1 Nef. The basic patch on micro1 that interacts with the Nef acidic cluster also contributes to the binding of endogenous acidic cluster proteins. PMID: 28743825
- CNNM4 is sorted to the basolateral membrane by the complementary function of AP-1A and AP-1B PMID: 25449265
- Adaptor protein 1 promotes cross-presentation through the same tyrosine signal in major histocompatibility complex class I as that targeted by HIV-1. PMID: 23678182
- IRS-1 associates with mu1A of the ubiquitously expressed AP-1 complex through three protein interaction motifs. PMID: 23478262
- Mu1A binding to the N terminus of HIV-1 Nef determines its ability to downregulate major histocompatibility complex class I in T lymphocytes. PMID: 22301137
- AP-1 mu1A is involved in the kAE1 trafficking of kidney alpha-intercalated cells PMID: 20833140
- These data identify the micro subunit of AP-1 (micro1) as the key target of the MHC-I CD/Nef complex, and they indicate that both Y320 in the MHC-I CD and E62-65 in Nef interact directly with micro1. PMID: 18057255
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亞細胞定位：Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
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蛋白家族：Adaptor complexes medium subunit family
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數(shù)據(jù)庫鏈接：
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