ALX1 Antibody, FITC conjugated
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中文名稱：ALX1兔多克隆抗體, FITC偶聯
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貨號：CSB-PA624031LC01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) ALX1 Polyclonal antibody
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Uniprot No.：
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基因名：ALX1
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別名：ALX homeobox 1 antibody; ALX homeobox protein 1 antibody; ALX1 antibody; ALX1_HUMAN antibody; CART 1 antibody; CART-1 antibody; CART1 antibody; Cartilage homeoprotein 1 antibody; Cartilage paired class homeoprotein 1 antibody; FND3 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human ALX homeobox protein 1 protein (10-304AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes. Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival. May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1.
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基因功能參考文獻：
- According to our analysis, three proteins, namely aristaless-like homeobox1 isoform X1 (ALX1), major histocompatibility complex polypeptide-related sequence A (MICA), and uncharacterized protein C14orf105 isoform X12 were found to be potential markers for Opisthorchis viverrini (OV)- infection, as they were predominantly found in all OV-infected groups PMID: 29936472
- Our study concludes that the splice site variant identified in the ALX1 gene causes mild form of Frontonasal dysplasia. PMID: 27324866
- we identify critical roles of ALX1 in lung cancer development and progression PMID: 26722397
- Knockdown of the CART1 gene significantly inhibited cell invasion and proliferation and induce cell cycle arrest in S phase. PMID: 27053613
- we found that depletion of ALX1 caused a dramatic cell cycle arrest, followed by massive apoptotic cell death, and eventually resulted in a significant decrease in migration and invasion of the osteosarcoma cell line studied. PMID: 25736924
- hypermethylation of HIST1H4F, PCDHGB6, NPBWR1, ALX1, and HOXA9 was significantly associated with shorter survival in stage 1 Non-small-cell lung cancer PMID: 24081945
- ALX1 upregulated expression of the key EMT regulator Snail (SNAI1) and that it mediated EMT activation and cell invasion by ALX1. PMID: 23288509
- Disruption of CART1 (ALX1) causes extreme microphthalmia and severe facial clefting. PMID: 20451171
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相關疾病：Frontonasal dysplasia 3 (FND3)
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亞細胞定位：Nucleus.
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蛋白家族：Paired homeobox family
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組織特異性：Cartilage and cervix tissue.
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數據庫鏈接：
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