AADAT Antibody

中文名稱：

AADAT兔多克隆抗體
貨號(hào)：

CSB-PA843276LA01HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA843276LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA843276LA01HU at dilution of 1:100
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
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靶點(diǎn)詳情

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) AADAT Polyclonal antibody
Uniprot No.：

Q8N5Z0
基因名：

AADAT
別名：

2 aminoadipate aminotransferase antibody; 2 aminoadipate transaminase antibody; 2-aminoadipate aminotransferase antibody; 2-aminoadipate transaminase antibody; Aadat antibody; AADAT_HUMAN antibody; Aadt antibody; AI875679 antibody; Alpha aminoadipate aminotransferase antibody; Alpha-aminoadipate aminotransferase antibody; Aminoadipate aminotransferase antibody; EC 2.6.1.39 antibody; EC 2.6.1.7 antibody; KAT/AadAT antibody; KAT2 antibody; KATII antibody; Kynurenine oxoglutarate transaminase 2 antibody; Kynurenine aminotransferase II antibody; Kynurenine oxoglutarate aminotransferase II antibody; Kynurenine oxoglutarate transaminase II antibody; Kynurenine--oxoglutarate aminotransferase II antibody; Kynurenine--oxoglutarate transaminase II antibody; Kynurenine/alpha-aminoadipate aminotransferase mitochondrial [Precursor] antibody; Kynurenine/alpha-aminoadipate aminotransferase; mitochondrial antibody; L kynurenine/alpha aminoadipate aminotransferase antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial protein (30-425AA)
免疫原種屬：

Homo sapiens (Human)

標(biāo)記方式：

Non-conjugated

本頁面中的產(chǎn)品，AADAT Antibody (CSB-PA843276LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于AADAT Antibody，我們還提供其他標(biāo)記。見下表：

標(biāo)記方式	貨號(hào)	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA843276LB01HU	AADAT Antibody, HRP conjugated	ELISA
FITC	CSB-PA843276LC01HU	AADAT Antibody, FITC conjugated
Biotin	CSB-PA843276LD01HU	AADAT Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro).
基因功能參考文獻(xiàn)：
1. Immunohistochemical analysis revealed the presence of KAT I, II, and III in all examined corneal sections. PMID: 28706436
2. he optimised method of protein production provides a fast and reliable technique to generate large quantities of active human KAT2 suitable for future small-molecule lead compound screening and structural design work. PMID: 26773745
3. Participants with major depression had lower levels of kynurenine compared to controls, with intermediate concentrations in somatoform patients. PMID: 24140252
4. Somatization is characterized by disorders in kynurenine aminotransferase activity and an increased neurotoxic potential PMID: 21712776
5. association of SNP AADAT+401C/T with the host immune response to bacterial meningitis, suggesting that this SNP may affect the host ability in recruitment of leukocytes to the infection site PMID: 21473761
6. analysis of the crystal structure of kynurenine aminotransferase II PMID: 18056995
7. analysis of the crystal structure of human kynurenine aminotransferase II PMID: 18056996
8. A human cDNA encodes a 425-residue protein with a mitochondrial cleavage signal and a pyridoxal-phosphate binding site, ~70% identical to the mouse and rat AADAT orthologs. Bacterial expression studies confirm that the gene encodes AADAT activity. PMID: 12126930
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亞細(xì)胞定位：

Mitochondrion.
蛋白家族：

Class-I pyridoxal-phosphate-dependent aminotransferase family
組織特異性：

Higher expression in the liver. Also found in heart, brain, kidney, pancreas, prostate, testis and ovary.
數(shù)據(jù)庫鏈接：

HGNC: 17929

OMIM: 611754

KEGG: hsa:51166

STRING: 9606.ENSP00000226840

UniGene: Hs.529735

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