AADAT Antibody
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中文名稱：AADAT兔多克隆抗體
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貨號：CSB-PA001019GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：AADAT
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別名：2 aminoadipate aminotransferase antibody; 2 aminoadipate transaminase antibody; 2-aminoadipate aminotransferase antibody; 2-aminoadipate transaminase antibody; Aadat antibody; AADAT_HUMAN antibody; Aadt antibody; AI875679 antibody; Alpha aminoadipate aminotransferase antibody; Alpha-aminoadipate aminotransferase antibody; Aminoadipate aminotransferase antibody; EC 2.6.1.39 antibody; EC 2.6.1.7 antibody; KAT/AadAT antibody; KAT2 antibody; KATII antibody; Kynurenine oxoglutarate transaminase 2 antibody; Kynurenine aminotransferase II antibody; Kynurenine oxoglutarate aminotransferase II antibody; Kynurenine oxoglutarate transaminase II antibody; Kynurenine--oxoglutarate aminotransferase II antibody; Kynurenine--oxoglutarate transaminase II antibody; Kynurenine/alpha-aminoadipate aminotransferase mitochondrial [Precursor] antibody; Kynurenine/alpha-aminoadipate aminotransferase; mitochondrial antibody; L kynurenine/alpha aminoadipate aminotransferase antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human AADAT
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro).
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基因功能參考文獻：
- Immunohistochemical analysis revealed the presence of KAT I, II, and III in all examined corneal sections. PMID: 28706436
- he optimised method of protein production provides a fast and reliable technique to generate large quantities of active human KAT2 suitable for future small-molecule lead compound screening and structural design work. PMID: 26773745
- Participants with major depression had lower levels of kynurenine compared to controls, with intermediate concentrations in somatoform patients. PMID: 24140252
- Somatization is characterized by disorders in kynurenine aminotransferase activity and an increased neurotoxic potential PMID: 21712776
- association of SNP AADAT+401C/T with the host immune response to bacterial meningitis, suggesting that this SNP may affect the host ability in recruitment of leukocytes to the infection site PMID: 21473761
- analysis of the crystal structure of kynurenine aminotransferase II PMID: 18056995
- analysis of the crystal structure of human kynurenine aminotransferase II PMID: 18056996
- A human cDNA encodes a 425-residue protein with a mitochondrial cleavage signal and a pyridoxal-phosphate binding site, ~70% identical to the mouse and rat AADAT orthologs. Bacterial expression studies confirm that the gene encodes AADAT activity. PMID: 12126930
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亞細胞定位：Mitochondrion.
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蛋白家族：Class-I pyridoxal-phosphate-dependent aminotransferase family
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組織特異性：Higher expression in the liver. Also found in heart, brain, kidney, pancreas, prostate, testis and ovary.
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數據庫鏈接：
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