WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1 is a protein in humans that is encoded by WWP1 gene. E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1; the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF.
WWP1 Antibodies
WWP1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA026167GA01HU | WWP1 Antibody | Human,Mouse,Rat | ELISA,WB |
WWP1 Proteins
WWP1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP806943MO CSB-EP806943MO CSB-BP806943MO CSB-MP806943MO CSB-EP806943MO-B |
Recombinant Mouse NEDD4-like E3 ubiquitin-protein ligase WWP1 (Wwp1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
WWP1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP872425HU CSB-EP872425HU CSB-BP872425HU CSB-MP872425HU CSB-EP872425HU-B |
Recombinant Human NEDD4-like E3 ubiquitin-protein ligase WWP1 (WWP1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
