VSIG4
VSIG4（V-set and immunoglobulin domain-containing 4，又稱為Complement receptor of the immunoglobulin superfamily，CRIg）是一種細(xì)胞表面蛋白，屬于免疫球蛋白超家族。它最初被發(fā)現(xiàn)是一種與補(bǔ)體系統(tǒng)相關(guān)的膜受體，在許多不同的細(xì)胞類型中都有表達(dá)，包括巨噬細(xì)胞、樹突狀細(xì)胞、中性粒細(xì)胞和肝細(xì)胞等，參與了多種生物學(xué)過程，包括免疫反應(yīng)、炎癥調(diào)節(jié)和腫瘤免疫治療等。作為一種膜受體，它可以與多種補(bǔ)體成分結(jié)合，包括C3b、iC3b和C1q等，從而調(diào)節(jié)免疫反應(yīng)的進(jìn)程。此外，VSIG4還可以作為一種調(diào)節(jié)炎癥反應(yīng)的受體，通過調(diào)節(jié)巨噬細(xì)胞的活化狀態(tài)來影響炎癥反應(yīng)的嚴(yán)重程度。
更多VSIG4相關(guān)閱讀：VSIG4：B7家族共刺激分子，補(bǔ)體系統(tǒng)或腫瘤藥開發(fā)創(chuàng)新靶點(diǎn)！
熱銷產(chǎn)品
驗(yàn)證數(shù)據(jù)
The purity was greater than 95% as determined by SDS-PAGE. (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Immobilized Human VSIG4 at 2 μg/ml can bind Anti-VSIG4 recombinant antibody (CSB-RA896869MA1HU), the EC50?is 51.14-68.73 ng/mL.
VSIG4 Antibodies
VSIG4 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA896869LA01HU | VSIG4 Antibody | Human | ELISA, IHC, IF |
| CSB-PA896869LB01HU | VSIG4 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA896869LC01HU | VSIG4 Antibody, FITC conjugated | Human | |
| CSB-PA896869LD01HU | VSIG4 Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA896869MA1HU | VSIG4 Recombinant Monoclonal Antibody | Human | ELISA |
VSIG4 Proteins
VSIG4 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP896869HU CSB-EP896869HU CSB-BP896869HU CSB-EP896869HU-B |
Recombinant Human V-set and immunoglobulin domain-containing protein 4 (VSIG4), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP896869HU | Recombinant Human V-set and immunoglobulin domain-containing protein 4 (VSIG4), partial (Active) | Mammalian cell |
VSIG4 ELISA Kit
VSIG4 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL025928HU | Human V-set and immunoglobulin domain-containing protein 4(VSIG4) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 7.81 pg/mL |
