TNR
Tenascin-R is a protein in humans that is encoded by TNR gene. Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components. These interactions can influence cellular behavior by either evoking a stable adhesion and differentiation, or repulsion and inhibition of neurite growth. Binding to cell surface gangliosides inhibits RGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2/FAK1 (FAK) phosphorylation and cell detachment. Binding to membrane surface sulfatides results in a oligodendrocyte adhesion and differentiation. Interaction with CNTN1 induces a repulsion of neurons and an inhibition of neurite outgrowth. Interacts with SCN2B may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier. TNR-linked chondroitin sulfate glycosaminoglycans are involved in the interaction with FN1 and mediate inhibition of cell adhesion and neurite outgrowth. The highly regulated addition of sulfated carbohydrate structure may modulate the adhesive properties of TNR over the course of development and during synapse maintenance (By similarity).
TNR Antibodies
TNR for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA024023GA01HU | TNR Antibody | Human | ELISA,WB,IHC |
| CSB-PA073278 | TNR Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA234912 | TNR Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA340307 | TNR Antibody | Human,Mouse,Rat | IHC,ELISA |
| CSB-PA340307LA01HU | TNR Antibody | Human | ELISA, IHC |
| CSB-PA340307LB01HU | TNR Antibody, HRP conjugated | Human | ELISA |
| CSB-PA340307LC01HU | TNR Antibody, FITC conjugated | Human | |
| CSB-PA340307LD01HU | TNR Antibody, Biotin conjugated | Human | ELISA |
TNR Proteins
TNR Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP803962MO CSB-EP803962MO CSB-BP803962MO CSB-MP803962MO CSB-EP803962MO-B |
Recombinant Mouse Tenascin-R (Tnr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TNR Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP852903HU CSB-EP852903HU CSB-BP852903HU CSB-MP852903HU CSB-EP852903HU-B |
Recombinant Human Tenascin-R (TNR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
