TIPARP
TIPARP，即TCDD誘導型聚(ADP-核糖)聚合酶，別名PARP7、ARTD14、pART14。TIPARP由人類TIPARP基因編碼，該基因位于3號染色體的q25.31區域。TIPARP是一種聚(ADP-核糖)聚合酶超家族的成員，它使用NAD+作為底物，將ADP-核糖轉移到蛋白質受體的谷氨酸殘基上；反復的ADP-核糖基化作用導致在蛋白質上形成聚鏈，從而改變目標蛋白的功能。TIPARP在多種生理過程中發揮作用，包括基因調控、病毒響應和細胞骨架調控。TIPARP的異常調控可能引起神經發育障礙、異常的抗病毒反應、某些類型的癌癥以及二惡英誘導的肝脂肪變性。
熱銷產品
Recombinant Human Protein mono-ADP-ribosyltransferase TIPARP (TIPARP) (CSB-BP801800HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TIPARP Antibody (CSB-PA801800LA01HU)
驗證數據
Western Blot
Positive WB detected in: U87 whole cell lysate, SH-SY5Y whole cell lysate
All lanes: TIPARP antibody at 4.6µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 77 kDa
Observed band size: 77 kDa
IHC image of CSB-PA801800LA01HU diluted at 1:300 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of CSB-PA801800LA01HU diluted at 1:300 and staining in paraffin-embedded human glioma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
TIPARP Antibodies
TIPARP for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA797551 | TIPARP Antibody | Human,Mouse | ELISA,WB |
| CSB-PA801800LA01HU | TIPARP Antibody | Human | ELISA, WB, IHC |
| CSB-PA801800LB01HU | TIPARP Antibody, HRP conjugated | Human | ELISA |
| CSB-PA801800LC01HU | TIPARP Antibody, FITC conjugated | Human | |
| CSB-PA801800LD01HU | TIPARP Antibody, Biotin conjugated | Human | ELISA |
TIPARP Proteins
TIPARP Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP801800HU CSB-MP801800HU CSB-EP801800HU-B |
Recombinant Human Protein mono-ADP-ribosyltransferase TIPARP (TIPARP) | Yeast Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP801800HU | Recombinant Human Protein mono-ADP-ribosyltransferase TIPARP (TIPARP) | E.coli |
| CSB-BP801800HU | Recombinant Human Protein mono-ADP-ribosyltransferase TIPARP (TIPARP) | Baculovirus |
