TH
Th，全稱為Tamm-Horsfall蛋白（THP），是一種由腎臟髓袢升支及遠(yuǎn)端小管曲部的上皮細(xì)胞合成分泌的糖蛋白。它也是尿液中含量最多的蛋白之一，常見別名包括T-H糖蛋白。在正常情況下，尿液中含有少量的THP，當(dāng)尿THP排出減少時(shí)，可能與腎實(shí)質(zhì)病變?nèi)缏阅I衰竭及急性腎小球腎炎等疾病有關(guān)，這些疾病會(huì)導(dǎo)致腎單位大量減少，從而使GFR顯著降低。相反，尿液THP含量增加則可能與間質(zhì)性腎炎、尿路長期梗阻、自身免疫性藥物中毒、銅和鉻中毒等疾病引起的腎臟損傷有關(guān)，且其含量變化與病情相一致。此外，THP在尿道結(jié)石患者體外震波碎石治療中，其含量變化也可用于治療效果的判斷。在藥物研發(fā)方面，雖然已有國外研究者報(bào)道了腎結(jié)石大鼠腎臟組織THP表達(dá)的結(jié)果，但治療因素干預(yù)下腎結(jié)石大鼠腎臟組織表達(dá)的研究尚未見報(bào)道，這為解析腎結(jié)石發(fā)病機(jī)理提供了新的研究方向。
熱銷產(chǎn)品
TH Antibody (CSB-PA023470LA01HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: A549 whole cell lysate, Hela whole cell lysate, Rat brain tissue, Rat liver tissue, Mouse liver tissue, Mouse brain tissue
All lanes: TH antibody at 4μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 59, 56, 57, 46, 45 kDa
Observed band size: 59 kDa
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA023470LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA023470LA01HU at dilution of 1:100
Human tyrosine hydroxylase,TH ELISA Kit (CSB-E09661h)
驗(yàn)證數(shù)據(jù)
貨號：CSB-E09661h
規(guī)格：96T/48T
靈敏度：0.078 ng/mL
檢測范圍：0.312 ng/mL-20 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
TH Antibodies
TH for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA154990 | Phospho-TH (Ser40) Antibody | Human,Mouse,Rat | ELISA,IF |
| CSB-PA439504 | Phospho-TH (Ser19) Antibody | Rat | ELISA,IF |
| CSB-PA695636 | TH (Ab-31) Antibody | Mouse,Rat | ELISA,WB |
| CSB-PA000731 | Phospho-TH (S19) Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA004284 | TH Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA004285 | TH Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA050254 | Phospho-TH (S62) Antibody | Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
| CSB-PA050255 | TH Antibody | Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
| CSB-PA011030 | Phospho-TH (S71) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA195276 | TH Antibody | Human | ELISA,IHC |
| CSB-PA903853 | TH Antibody | Human | ELISA,IHC |
| CSB-PA023470LA01HU | TH Antibody | Human, Mouse, Rat | ELISA, WB, IHC |
| CSB-PA023470LB01HU | TH Antibody, HRP conjugated | Human | ELISA |
| CSB-PA023470LC01HU | TH Antibody, FITC conjugated | Human | |
| CSB-PA023470LD01HU | TH Antibody, Biotin conjugated | Human | ELISA |
TH for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA004286 | TH Antibody | Rat | WB, IHC, ELISA |
| CSB-PA006345 | Phospho-TH (S8) Antibody | Rat | WB, IHC, ELISA |
TH Proteins
TH Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP023470HU CSB-EP023470HU CSB-BP023470HU CSB-MP023470HU CSB-EP023470HU-B |
Recombinant Human Tyrosine 3-monooxygenase (TH) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TH ELISA Kit
TH ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E09661h | Human tyrosine hydroxylase,TH ELISA Kit | serum, plasma, tissue homogenates | 0.078 ng/mL |
