SUCNR1
SUCNR1，即糖原合酶1，別名Succinate receptor 1 Curated、G-protein coupled receptor 91、P2Y purinoceptor 1-like，它是一種在細(xì)胞糖原合成過程中發(fā)揮關(guān)鍵作用的酶。SUCNR1在多種生物體中都有發(fā)現(xiàn)，包括人類、動(dòng)物、植物和微生物。它的作用機(jī)制主要是通過催化糖原合成過程中的最后一個(gè)步驟，即將UDPG（尿苷二磷酸葡萄糖）轉(zhuǎn)移到糖原鏈上，從而延長(zhǎng)糖原分子。SUCNR1的活性受到多種因素的調(diào)控，包括營(yíng)養(yǎng)狀態(tài)、激素水平和細(xì)胞內(nèi)信號(hào)分子等。SUCNR1在生物學(xué)上的意義主要體現(xiàn)在其對(duì)細(xì)胞能量代謝的調(diào)控作用。作為糖原合成的關(guān)鍵酶，SUCNR1參與了細(xì)胞對(duì)葡萄糖的儲(chǔ)存和釋放過程，維持了血糖水平的穩(wěn)定。此外，SUCNR1還參與了多種信號(hào)通路，包括胰島素信號(hào)通路、AMPK（AMP依賴性蛋白激酶）信號(hào)通路等，這些信號(hào)通路對(duì)細(xì)胞的生長(zhǎng)、分化和代謝都有著重要的影響。SUCR1的功能異常與多種疾病相關(guān)，如糖尿病、肥胖和某些遺傳性糖原貯積病等，因此，SUCNR1也是藥物開發(fā)中的一個(gè)潛在靶點(diǎn)。
熱銷產(chǎn)品
Recombinant Human Succinate receptor 1 (SUCNR1) (CSB-CF022921HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
SUCNR1 Antibodies
SUCNR1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA040022 | SUCNR1 Antibody | Human,Mouse,Rat | WB, IF, ELISA |
| CSB-PA022921LA01HU | SUCNR1 Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA022921LB01HU | SUCNR1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA022921LC01HU | SUCNR1 Antibody, FITC conjugated | Human | |
| CSB-PA022921LD01HU | SUCNR1 Antibody, Biotin conjugated | Human | ELISA |
SUCNR1 Proteins
SUCNR1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP022921RA1 CSB-EP022921RA1 CSB-BP022921RA1 CSB-MP022921RA1 CSB-EP022921RA1-B |
Recombinant Rat Succinate receptor 1 (Sucnr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF022921RA | Recombinant Rat Succinate receptor 1 (Sucnr1) | in vitro E.coli expression system |
SUCNR1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP022921MO1 CSB-EP022921MO1 CSB-BP022921MO1 CSB-MP022921MO1 CSB-EP022921MO1-B |
Recombinant Mouse Succinate receptor 1 (Sucnr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF022921MO | Recombinant Mouse Succinate receptor 1 (Sucnr1) | in vitro E.coli expression system |
SUCNR1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP022921HU1 CSB-EP022921HU1 CSB-BP022921HU1 CSB-MP022921HU1 CSB-EP022921HU1-B |
Recombinant Human Succinate receptor 1 (SUCNR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF022921HU | Recombinant Human Succinate receptor 1 (SUCNR1) | in vitro E.coli expression system |
| CSB-MP022921HU | Recombinant Human Succinate receptor 1 (SUCNR1)-VLPs | Mammalian cell |
