SPATA13
Spermatogenesis-associated protein 13 is a protein in humans that is encoded by SPATA13 gene. Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
SPATA13 Antibodies
SPATA13 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA022491GA01HU | SPATA13 Antibody | Human,Mouse,Rat | ELISA,WB,IF |
| CSB-PA559431 | SPATA13 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA583273 | SPATA13 Antibody | Human,Mouse | ELISA,WB,IHC |
SPATA13 Proteins
SPATA13 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP701751MO CSB-EP701751MO CSB-BP701751MO CSB-MP701751MO CSB-EP701751MO-B |
Recombinant Mouse Spermatogenesis-associated protein 13 (Spata13) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SPATA13 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP842724HU CSB-EP842724HU CSB-BP842724HU CSB-MP842724HU CSB-EP842724HU-B |
Recombinant Human Spermatogenesis-associated protein 13 (SPATA13) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
