SMAD7
Mothers against decapentaplegic homolog 7 is a protein in humans that is encoded by SMAD7 gene. Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
SMAD7 Antibodies
SMAD7 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA950035 | SMAD7 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA324386 | SMAD7 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA021793LA01HU | SMAD7 Antibody | Human | ELISA, WB, IF |
| CSB-PA021793LB01HU | SMAD7 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA021793LC01HU | SMAD7 Antibody, FITC conjugated | Human | |
| CSB-PA021793LD01HU | SMAD7 Antibody, Biotin conjugated | Human | ELISA |
SMAD7 Proteins
SMAD7 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP021793HU CSB-EP021793HU CSB-BP021793HU CSB-MP021793HU CSB-EP021793HU-B |
Recombinant Human Mothers against decapentaplegic homolog 7 (SMAD7) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SMAD7 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP021793MO CSB-EP021793MO CSB-BP021793MO CSB-MP021793MO CSB-EP021793MO-B |
Recombinant Mouse Mothers against decapentaplegic homolog 7 (Smad7) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SMAD7 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP021793RA CSB-EP021793RA CSB-BP021793RA CSB-MP021793RA CSB-EP021793RA-B |
Recombinant Rat Mothers against decapentaplegic homolog 7 (Smad7) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
