SAGE1
div class=margin-large-bottom p class=margin-big-bottomSAGE1(Sarcoma Antigen 1)是一種腫瘤睪丸抗原基因,其在多種腫瘤組織中的表達量通常比癌旁組織高,顯示出與細胞增生有密切關系。SAGE1與INTS6(Integrator 6)競爭INTS3(Integrator 3),通過破壞阻礙RNA聚合酶II的“剎車”機制,新形成的INTS3-SAGE1復合物與基因靶標的啟動子-近端區域結合,從而激活癌癥相關途徑中的基因轉錄。這一過程最終會導致細胞增殖,促進腫瘤的生長和擴散。SAGE1通過影響細胞生長、增殖和分化等關鍵過程的信號通路,在癌癥的發生和發展中發揮重要作用。p h2 class=margin-large-top熱銷產品h2 pa href=httpswww.tzmingka.cnRecombinant-ProteinsRecombinant-Human-Sarcoma-antigen-1(SAGE1)--partial-677682.htmlRecombinant Human Sarcoma antigen 1 (SAGE1), partialap div class=card card-5n div class=card-item border margin-big-bottom div class=boldtxt text-center bg-gray-light padding-small head size13CSB-YP20670HUdiv div class=text-center padding p來源:Yeastp div div div class=card-item border margin-big-bottom div class=boldtxt text-center bg-gray-light padding-small head size13CSB-EP20670HUdiv div class=text-center padding p來源:E.colip div div div class=card-item border margin-big-bottom div class=boldtxt text-center bg-gray-light padding-small head size13CSB-BP20670HUdiv div class=text-center padding p來源:Baculovirusp div div div class=card-item border margin-big-bottom div class=boldtxt text-center bg-gray-light padding-small head size13CSB-MP20670HUdiv div class=text-center padding p來源:Mammalian cellp div div div class=card-item border margin-big-bottom div class=boldtxt text-center bg-gray-light padding-small head size13CSB-EP20670HU-Bdiv div class=text-center padding p來源:In Vivo Biotinylation in E.colip div div div div br
SAGE1 Antibodies
SAGE1 for Homo sapiens (Human)
產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
---|---|---|---|
CSB-PA020670LA01HU | SAGE1 Antibody | Human | ELISA, IHC |
CSB-PA020670LB01HU | SAGE1 Antibody, HRP conjugated | Human | ELISA |
CSB-PA020670LC01HU | SAGE1 Antibody, FITC conjugated | Human | |
CSB-PA020670LD01HU | SAGE1 Antibody, Biotin conjugated | Human | ELISA |
SAGE1 Proteins
SAGE1 Proteins for Homo sapiens (Human)
產品貨號 | 產品名稱 | 來源 |
---|---|---|
CSB-YP020670HU CSB-EP020670HU CSB-BP020670HU CSB-MP020670HU CSB-EP020670HU-B |
Recombinant Human Sarcoma antigen 1 (SAGE1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |