S100A11
S100A11，即S100鈣結(jié)合蛋白A11，別名S100a11、S100C。它是一種低分子量（10-14 kDa）的鈣離子結(jié)合蛋白，屬于S100蛋白家族。S100A11在多種組織中表達(dá)，可位于細(xì)胞質(zhì)、細(xì)胞核，甚至細(xì)胞外圍，通常以非共價鍵形成的同源二聚體存在。S100A11的作用機(jī)制涉及其與Ca2+的結(jié)合，這種結(jié)合觸發(fā)構(gòu)象變化，暴露出疏水口袋，從而促進(jìn)與靶蛋白的相互作用。S100A11通過與多種靶蛋白結(jié)合，在多種生物學(xué)過程中發(fā)揮作用，包括調(diào)節(jié)細(xì)胞生長、凋亡、炎癥反應(yīng)和細(xì)胞骨架構(gòu)建等。S100A11參與多種細(xì)胞活性及功能調(diào)控。它在調(diào)節(jié)細(xì)胞生長和凋亡、參與炎癥反應(yīng)、細(xì)胞膜修復(fù)及DNA修復(fù)等生物學(xué)功能中發(fā)揮作用。S100A11還參與癌癥的發(fā)生發(fā)展，其在多種腫瘤中高表達(dá)，并且與某些癌癥患者的不良預(yù)后有關(guān)。
熱銷產(chǎn)品
S100A11 Antibody (CSB-PA625010)
驗證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA625010(S100A11 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hepg2 cells, A549 cells, Primary antibody: CSB-PA625010(S100A11 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 seconds
S100A11 Antibodies
S100A11 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA020624GA01HU | S100A11 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA040286 | S100A11 Antibody | Human,Mouse,Rat | IHC, ELISA |
| CSB-PA592500 | S100A11 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA625010 | S100A11 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA020624HA01HU | S100A11 Antibody | Human | ELISA, IHC |
| CSB-PA020624HD01HU | S100A11 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA020624HC01HU | S100A11 Antibody, FITC conjugated | Human | |
| CSB-PA020624HB01HU | S100A11 Antibody, HRP conjugated | Human | ELISA |
S100A11 Proteins
S100A11 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP020624HU CSB-BP020624HU CSB-MP020624HU CSB-EP020624HU-B |
Recombinant Human Protein S100-A11 (S100A11) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP020624HU | Recombinant Human Protein S100-A11 (S100A11) | E.coli |
S100A11 ELISA Kit
S100A11 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E15827h | Human S100 Calcium Binding Protein A11(S100A11) ELISA Kit | serum, plasma, tissue homogenates, cell lysates | 0.039 ng/mL |
