ROR2
ROR2，即受體酪氨酸激酶樣孤兒受體2，別名ROR2、MFNG等。它是一種由ROR2基因編碼的跨膜蛋白，屬于ROR家族成員，在多種細(xì)胞類型中表達(dá)。ROR2的作用機(jī)制涉及與Wnt5A等配體結(jié)合，激活非經(jīng)典Wnt/PCP信號(hào)通路，參與調(diào)控細(xì)胞遷移、增殖和極性。ROR2的功能異常與某些疾病有關(guān)，如骨骼發(fā)育異常、腫瘤發(fā)展等。ROR2在腫瘤細(xì)胞中的異常表達(dá)可能促進(jìn)腫瘤的侵襲和轉(zhuǎn)移，使其成為癌癥治療的潛在靶點(diǎn)。
熱銷產(chǎn)品
ROR2 Recombinant Monoclonal Antibody (CSB-RA932279MA1HU)
驗(yàn)證數(shù)據(jù)
IHC image of CSB-RA932279MA1HU diluted at 1：100 and staining in paraffin-embedded human ovarian tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB.
ROR2 Antibodies
ROR2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA020176 | ROR2 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA21119A0Rb | ROR2 Antibody | Human | ELISA, IHC, IF |
| CSB-PA21119B0Rb | ROR2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA21119C0Rb | ROR2 Antibody, FITC conjugated | Human | |
| CSB-PA21119D0Rb | ROR2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA932279MA1HU | ROR2 Recombinant Monoclonal Antibody | Human | ELISA, IHC |
