RNASEH1
RNASEH1（Ribonuclease H1）是核糖核酸內(nèi)切酶H1內(nèi)切酶。RNASEH1的主要功能是在DNA修復(fù)過程中起作用，特別是在RNA-DNA雜交物的剪切中。它有助于維持基因組穩(wěn)定性，通過消除RNA與DNA的雜交，防止不必要的雜交結(jié)構(gòu)的累積，并保持細(xì)胞的正常功能。研究表明，RNASEH1的突變或缺陷與一種罕見的遺傳性神經(jīng)系統(tǒng)退行性疾病——Aicardi-Goutières綜合征（AGS）相關(guān)。AGS通常伴隨著神經(jīng)系統(tǒng)發(fā)育異常和免疫系統(tǒng)異常，而RNASEH1的異?？赡芘c此類癥狀的出現(xiàn)有關(guān)。此外，RNASEH1在細(xì)胞生物學(xué)研究和RNA-DNA雜交相關(guān)領(lǐng)域也具有重要的應(yīng)用潛力。對(duì)RNASEH1的深入研究不僅有助于理解細(xì)胞的核酸代謝和基因組穩(wěn)定性的維持，還可能為治療相關(guān)疾病提供新的治療方法或干預(yù)手段。
熱銷產(chǎn)品
Recombinant Human Ribonuclease H1 (RNASEH1)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP019801HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) RNASEH1.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP019801HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) RNASEH1.
RNASEH1 Antibodies
RNASEH1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA019801GA01HU | RNASEH1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA019801LA01HU | RNASEH1 Antibody | Human | ELISA, WB, IHC |
| CSB-PA019801LB01HU | RNASEH1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA019801LC01HU | RNASEH1 Antibody, FITC conjugated | Human | |
| CSB-PA019801LD01HU | RNASEH1 Antibody, Biotin conjugated | Human | ELISA |
RNASEH1 Proteins
RNASEH1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP019801MO CSB-EP019801MO CSB-BP019801MO CSB-MP019801MO CSB-EP019801MO-B |
Recombinant Mouse Ribonuclease H1 (Rnaseh1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RNASEH1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP019801HU CSB-BP019801HU CSB-MP019801HU CSB-EP019801HU-B |
Recombinant Human Ribonuclease H1 (RNASEH1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP019801HU | Recombinant Human Ribonuclease H1 (RNASEH1) | E.coli |
| CSB-EP019801HUc7 | Recombinant Human Ribonuclease H1 (RNASEH1) | E.coli |
