RET
RET是受體酪氨酸激酶家族的一員，其結構包含細胞外域、跨膜域、酪氨酸激酶域和羧基末端。RET通過與特定配體結合，激活其胞內區的酪氨酸激酶活性，進而啟動下游信號轉導通路，影響細胞的生長、增殖、分化和凋亡等生物學過程。RET在維持多種細胞類型如神經細胞、內分泌細胞和腎臟細胞的正常功能中發揮著重要作用。然而，當RET基因發生突變或異常表達時，可能導致疾病的發生，如甲狀腺髓樣癌等。因此，對RET的結構、功能和生物學作用的研究不僅有助于我們理解其在正常生理過程中的作用，也為相關疾病的預防和治療提供了新的視角和策略。
熱銷產品
RET Recombinant Monoclonal Antibody (CSB-RA288083A0HU)
驗證數據
Overlay histogram showing Hela cells stained with CSB-RA288083A0HU (red line) at 1:50. The cells were fixed in 4% formaldehyde (15min) and permeated by 0.2% TritonX-100 for 10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*106cells) for 45min at 4℃.The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 30min at 4℃. Control antibody (green line) was Rabbit IgG (1μg/1*106 cells) used under the same conditions. Acquisition of >10,000 events was performed.
RET Antibodies
RET for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA019572DSR1HU | RET Antibody | Human | ELISA, WB, IHC |
| CSB-PA019572DSR2HU | RET Antibody | Human | ELISA, IHC |
| CSB-PA003961 | RET Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA003963 | RET Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA040202 | Phospho-RET (Y1015) Antibody | Human,Mouse,Rat,Monkey | WB, ELISA |
| CSB-PA040203 | Phospho-RET (Y1062) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA040204 | Phospho-RET (Y905) Antibody | Human,Mouse,Rat | IHC, IF, ELISA |
| CSB-RA288083A0HU | RET Recombinant Monoclonal Antibody | Human | ELISA, FC |
RET Proteins
RET Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP019572HU CSB-EP019572HU CSB-BP019572HU CSB-MP019572HU CSB-EP019572HU-B |
Recombinant Human Proto-oncogene tyrosine-protein kinase receptor Ret (RET), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
