RBL1
Retinoblastoma-like protein 1 is a protein in humans that is encoded by RBL1 gene. Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation. Forms a complex with adenovirus E1A and with SV40 large T antigen. May bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. May act as a tumor suppressor.
RBL1 Antibodies
RBL1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA019398GA01HU | RBL1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA040182 | Phospho-RBL1 (T369) Antibody | Human,Mouse | IHC, ELISA |
| CSB-PA040183 | RBL1 Antibody | Human,Mouse | IF, ELISA |
| CSB-PA019398LA01HU | RBL1 Antibody | Human, Mouse | ELISA, WB |
| CSB-PA019398LB01HU | RBL1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA019398LC01HU | RBL1 Antibody, FITC conjugated | Human | |
| CSB-PA019398LD01HU | RBL1 Antibody, Biotin conjugated | Human | ELISA |
RBL1 Proteins
RBL1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP019398HU CSB-EP019398HU CSB-BP019398HU CSB-MP019398HU CSB-EP019398HU-B |
Recombinant Human Retinoblastoma-like protein 1 (RBL1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RBL1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP717574MO CSB-EP717574MO CSB-BP717574MO CSB-MP717574MO CSB-EP717574MO-B |
Recombinant Mouse Retinoblastoma-like protein 1 (Rbl1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
