PTPRB
Receptor-type tyrosine-protein phosphatase beta is a protein in humans that is encoded by PTPRB gene. Plays an important role in blood vessel remodeling and angiogenesis. Not necessary for the initial formation of blood vessels, but is essential for their maintenance and remodeling. Can induce dephosphorylation of TEK/TIE2, CDH5/VE-cadherin and KDR/VEGFR-2. Regulates angiopoietin-TIE2 signaling in endothelial cells. Acts as a negative regulator of TIE2, and controls TIE2 driven endothelial cell proliferation, which in turn affects blood vessel remodeling during embryonic development and determines blood vessel size during perinatal growth. Essential for the maintenance of endothelial cell contact integrity and for the adhesive function of VE-cadherin in endothelial cells and this requires the presence of plakoglobin (By similarity).
PTPRB Antibodies
PTPRB for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA019048ESR2HU | PTPRB Antibody | Human | ELISA, IHC |
PTPRB Proteins
PTPRB Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP019048HU | Recombinant Human Receptor-type tyrosine-protein phosphatase beta (PTPRB), partial | Yeast |
| CSB-EP019048HU | Recombinant Human Receptor-type tyrosine-protein phosphatase beta (PTPRB), partial | E.coli |
| CSB-BP019048HU CSB-MP019048HU CSB-EP019048HU-B |
Recombinant Human Receptor-type tyrosine-protein phosphatase beta (PTPRB), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PTPRB Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP019048MO CSB-EP019048MO CSB-BP019048MO CSB-MP019048MO CSB-EP019048MO-B |
Recombinant Mouse Receptor-type tyrosine-protein phosphatase beta (Ptprb), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
