PTGS1
PTGS1，即前列腺素內(nèi)過氧化物合酶1，別名COX1、PGHS1、PHS1等。這是一種在人體中的酶，主要在9號(hào)染色體上表達(dá)。PTGS1的作用機(jī)制是通過催化花生四烯酸合成前列腺素H2（PGH2），這是所有前列腺素和血栓素的前體。前列腺素是一類具有多種生理作用的生物活性物質(zhì)，包括調(diào)節(jié)炎癥反應(yīng)、疼痛感知、發(fā)熱以及血小板聚集等。PTGS1對(duì)于維持正常生理功能至關(guān)重要，但其異常表達(dá)也與多種疾病相關(guān)，尤其是與炎癥和腫瘤發(fā)生發(fā)展有關(guān)。例如，PTGS1的高表達(dá)與腫瘤細(xì)胞的增殖和抗凋亡能力增強(qiáng)相關(guān)，因此它也是許多非甾體抗炎藥和抗癌藥物的作用靶點(diǎn)。
熱銷產(chǎn)品
PTGS1 Recombinant Monoclonal Antibody (CSB-RA918236A0HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: HL60 whole cell lysate, SH-SY5Y whole cell lysate, Mouse liver tissue
All lanes: PTGS1 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 69, 65, 62, 57, 72, 73 kDa
Observed band size: 72 kDa
Overlay histogram showing Hela cells stained with CSB-RA918236A0HU (red line) at 1:50. The cells were fixed with 70% Ethylalcohol (18h) and then incubated in 10% normal goat serum to block non-specific protein-protein interactions followedby the antibody (1μg/1*106 cells) for 1 h at 4℃.The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 30min at 4℃. Control antibody (green line) was Rabbit IgG (1μg/1*106 cells) used under the same conditions. Acquisition of >10,000 events was performed.
PTGS1 Antibodies
PTGS1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA164506 | PTGS1 Antibody | Human | ELISA,WB,IHC |
| CSB-PA000360 | PTGS1 Antibody | Human | WB |
| CSB-PA001761 | PTGS1 Antibody | Human | WB, IHC, ELISA |
| CSB-PA035390 | PTGS1 Antibody | Human | ELISA,IHC |
| CSB-RA918236A0HU | PTGS1 Recombinant Monoclonal Antibody | Human, Mouse | ELISA, WB, FC |
PTGS1 Proteins
PTGS1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP018985HU CSB-BP018985HU CSB-MP018985HU CSB-EP018985HU-B |
Recombinant Human Prostaglandin G/H synthase 1 (PTGS1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP018985HU | Recombinant Human Prostaglandin G/H synthase 1 (PTGS1) | E.coli |
| CSB-EP018985HUa0 | Recombinant Human Prostaglandin G/H synthase 1 (PTGS1) | E.coli |
