PRKCQ
Protein kinase C theta type is a protein in humans that is encoded by PRKCQ gene. Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that mediates non-redundant functions in T-cell receptor (TCR) signaling, including T-cells activation, proliferation, differentiation and survival, by mediating activation of multiple transcription factors such as NF-kappa-B, JUN, NFATC1 and NFATC2. In TCR-CD3/CD28-co-stimulated T-cells, is required for the activation of NF-kappa-B and JUN, which in turn are essential for IL2 production, and participates in the calcium-dependent NFATC1 and NFATC2 transactivation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11 on several serine residues, inducing CARD11 association with lipid rafts and recruitment of the BCL10-MALT1 complex, which then activates IKK complex, resulting in nuclear translocation and activation of NFKB1.
PRKCQ Antibodies
PRKCQ for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA160849 | Phospho-PRKCQ (Ser695) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA075054 | Phospho-PRKCQ (Ser676) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA798681 | PRKCQ (Ab-676) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA443202 | PRKCQ (Ab-695) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA593320 | PRKCQ Antibody | Human | ELISA,IHC |
| CSB-PA030269 | Phospho-PRKCQ (S676) Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA030270 | Phospho-PRKCQ (T538) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA030271 | Phospho-PRKCQ (S695) Antibody | Human | WB, IHC, ELISA |
| CSB-PA030272 | PRKCQ Antibody | Human | IHC, ELISA |
| CSB-PA030273 | PRKCQ Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA030274 | PRKCQ Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-RA978159A0HU | PRKCQ Recombinant Monoclonal Antibody | Human, Mouse | ELISA, WB |
PRKCQ Proteins
PRKCQ Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP894347RA CSB-EP894347RA CSB-BP894347RA CSB-MP894347RA CSB-EP894347RA-B |
Recombinant Rat Protein kinase C theta type (Prkcq) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
