PRAME
PRAME，全稱為“黑色素瘤優(yōu)先表達抗原”，是一種在黑色素瘤細胞中高度表達的腫瘤相關抗原。它也被稱為“PRAME蛋白”，在醫(yī)學研究中，它被用作診斷和鑒別黑色素細胞腫瘤的可靠標記物。PRAME蛋白在正常組織中僅限于睪丸、卵巢、皮脂腺、腎上腺等少數部位表達。在藥物研發(fā)方面，PRAME蛋白作為靶點的研究正在推進，旨在開發(fā)針對多種實體瘤的治療方法。例如，針對PRAME蛋白的雙特異性抗體和TCR-T細胞療法在黑色素瘤等癌癥的治療中顯示出潛力。
熱銷產品
Recombinant Human Melanoma antigen preferentially expressed in tumors (PRAME) (CSB-YP018603HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP018603HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) PRAME.
Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP018603HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) PRAME.
PRAME Antibody (CSB-PA018603LA01HU)
驗證數據
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA018603LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA018603LA01HU at dilution of 1:100
PRAME Antibodies
PRAME for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA018603LA01HU | PRAME Antibody | Human | ELISA, IHC |
| CSB-PA018603LB01HU | PRAME Antibody, HRP conjugated | Human | ELISA |
| CSB-PA018603LC01HU | PRAME Antibody, FITC conjugated | Human | |
| CSB-PA018603LD01HU | PRAME Antibody, Biotin conjugated | Human | ELISA |
PRAME Proteins
PRAME Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018603HU | Recombinant Human Melanoma antigen preferentially expressed in tumors (PRAME) | Yeast |
| CSB-EP018603HU | Recombinant Human Melanoma antigen preferentially expressed in tumors (PRAME) | E.coli |
| CSB-BP018603HU CSB-MP018603HU CSB-EP018603HU-B |
Recombinant Human Melanoma antigen preferentially expressed in tumors (PRAME) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
