PIAS4
E3 SUMO-protein ligase PIAS4 is a protein in humans that is encoded by PIAS4 gene. Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Mediates sumoylation of CEBPA, PARK7, HERC2, MYB, TCF4 and RNF168. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation.
PIAS4 Antibodies
PIAS4 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA017960GA01HU | PIAS4 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA577177 | PIAS4 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA030004 | PIAS4 Antibody | Human,Mouse | WB, IHC, ELISA |
| CSB-PA822692LA01HU | PIAS4 Antibody | Human | ELISA, IHC |
| CSB-PA822692LB01HU | PIAS4 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA822692LC01HU | PIAS4 Antibody, FITC conjugated | Human | |
| CSB-PA822692LD01HU | PIAS4 Antibody, Biotin conjugated | Human | ELISA |
PIAS4 Proteins
PIAS4 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP822692HU CSB-EP822692HU CSB-BP822692HU CSB-MP822692HU CSB-EP822692HU-B |
Recombinant Human E3 SUMO-protein ligase PIAS4 (PIAS4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIAS4 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP878109MO CSB-EP878109MO CSB-BP878109MO CSB-MP878109MO CSB-EP878109MO-B |
Recombinant Mouse E3 SUMO-protein ligase PIAS4 (Pias4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
