PCCB
PCCB，全稱為丙酰輔酶A羧化酶β鏈蛋白，也被稱為PCCβ。它在人體內(nèi)參與丙酰輔酶A的合成，對(duì)于氨基酸和脂質(zhì)的分解代謝至關(guān)重要。PCCB蛋白的異常可能導(dǎo)致丙酸血癥，這是一種罕見的遺傳代謝疾病。目前，針對(duì)PCCB蛋白的研究主要集中在利用基因編輯技術(shù)構(gòu)建基因敲除的細(xì)胞模型，以研究丙酸血癥的發(fā)病機(jī)制。此外，研究人員也在探索通過補(bǔ)充PCCB蛋白或其相關(guān)藥物來(lái)治療丙酸血癥，以期改善患者的癥狀。
熱銷產(chǎn)品
Recombinant Human Propionyl-CoA carboxylase beta chain, mitochondrial (PCCB) (CSB-EP017523HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
PCCB Antibody (CSB-PA017523LA01HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: Jurkat whole cell lysate
All lanes: PCCB antibody at 7.7µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 59, 61 kDa
Observed band size: 59 kDa
IHC image of CSB-PA017523LA01HU diluted at 1:300 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of CSB-PA017523LA01HU diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
PCCB Antibodies
PCCB for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA017523LA01HU | PCCB Antibody | Human | ELISA, WB, IHC |
| CSB-PA017523LB01HU | PCCB Antibody, HRP conjugated | Human | ELISA |
| CSB-PA017523LC01HU | PCCB Antibody, FITC conjugated | Human | |
| CSB-PA017523LD01HU | PCCB Antibody, Biotin conjugated | Human | ELISA |
PCCB Proteins
PCCB Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP017523HU CSB-BP017523HU CSB-MP017523HU CSB-EP017523HU-B |
Recombinant Human Propionyl-CoA carboxylase beta chain, mitochondrial (PCCB) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP017523HU | Recombinant Human Propionyl-CoA carboxylase beta chain, mitochondrial (PCCB) | E.coli |
