NRP2
神經(jīng)纖毛蛋白2（NRP2）是一種跨膜糖蛋白，在細胞表面發(fā)揮多重功能。它通常被稱為neuropilin-2，在多種生理過程中發(fā)揮作用，包括血管生成、神經(jīng)發(fā)育和細胞遷移。NRP2能夠與多種生長因子和細胞因子結(jié)合，如血管內(nèi)皮生長因子（VEGF）和神經(jīng)生長因子，從而促進血管生成和細胞遷移。此外，NRP2還參與軸突導向、淋巴管生成、血管發(fā)育及神經(jīng)嵴細胞遷移等過程。在疾病方面，NRP2的異常表達與多種癌癥的進展、神經(jīng)系統(tǒng)疾病以及心血管疾病相關。例如，在癌癥中，NRP2的高表達與腫瘤的侵襲性、轉(zhuǎn)移性和耐藥性增加有關。在神經(jīng)系統(tǒng)疾病中，NRP2的異常表達與神經(jīng)退行性疾病和神經(jīng)損傷相關。在心血管疾病中，NRP2的高表達與動脈粥樣硬化和血管狹窄相關。針對NRP2的藥物研發(fā)主要集中在抑制其與VEGF等配體的結(jié)合，以阻斷腫瘤血管生成和細胞遷移。此外，NRP2也被視為治療自身免疫性疾病和神經(jīng)退行性疾病的潛在靶點。
熱銷產(chǎn)品
NRP2 Antibody (CSB-PA016092LA01HU)
驗證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA016092LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA016092LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA016092LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Human Neuropilin-2(NRP2) ELISA kit (CSB-EL016092HU)
驗證數(shù)據(jù)
貨號：CSB-EL016092HU
規(guī)格：96T/48T
靈敏度：0.078 ng/mL
檢測范圍：0.312 ng/mL-20 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
NRP2 Antibodies
NRP2 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA005175 | NRP2 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA070153 | NRP2 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA255815 | NRP2 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA563181 | NRP2 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA016092LA01HU | NRP2 Antibody | Human | ELISA, IHC, IF |
| CSB-PA016092LC01HU | NRP2 Antibody, FITC conjugated | Human | |
| CSB-PA016092LD01HU | NRP2 Antibody, Biotin conjugated | Human | ELISA |
NRP2 Proteins
NRP2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP016092HU CSB-EP016092HU CSB-BP016092HU CSB-MP016092HU CSB-EP016092HU-B |
Recombinant Human Neuropilin-2 (NRP2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NRP2 ELISA Kit
NRP2 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL016092HU | Human Neuropilin-2(NRP2) ELISA kit | serum, plasma, tissue homogenates | 0.078 ng/mL |
