NES
NES，全名為核輸出序列蛋白，也被稱為核輸出序列。該蛋白在細胞核與細胞質之間的蛋白質運輸中發揮關鍵作用。NES蛋白通過識別并結合特定的核定位信號，將蛋白質從細胞核通過核孔復合體運輸到細胞質。這一過程對于維持細胞內蛋白質平衡和細胞功能至關重要。NES蛋白的異常與多種疾病相關，包括腫瘤、神經退行性疾病等。在藥物研發方面，針對NES蛋白的藥物正在研發中，旨在治療與NES蛋白功能異常相關的疾病。
熱銷產品
Recombinant Human Nestin (NES), partial (CSB-YP015713HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
NES Monoclonal Antibody (CSB-MA0157131A0m)
驗證數據
Western Blot
Positive WB detected in: U251 whole cell lysate, SH-SY5Y whole cell lysate
All lanes: NES antibody at 3µg/ml
Secondary
Goat polyclonal to Mouse IgG at 1/10000 dilution
Predicted band size: 178 kDa
Observed band size: 260 kDa
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-MA0157131A0m at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-MA0157131A0m at dilution of 1:100
Immunohistochemistry of paraffin-embedded human melanoma using CSB-MA0157131A0m at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSB-MA0157131A0m at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Mouse IgG(H+L).
Immunofluorescent analysis of PC-3 cells using CSB-MA0157131A0m at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Mouse IgG(H+L).
Immunofluorescent analysis of U251 cells using CSB-MA0157131A0m at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Mouse IgG(H+L).
Overlay histogram showing U251 cells stained with CSB-MA0157131A0m (red line). The cells were fixed with 70% Ethylalcohol (18h) and then permeabilized with 0.3% Triton X-100 for 2 min. The cells were then incubated in 1x PBS /10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (10µg/1*106cells) for 1 h at 4°C. The secondary antibody used was FITC goat anti-mouse IgG(H+L) at 1/200 dilution for 1 h at 4°C. Isotype control antibody (green line) was mouse IgG1 (10µg/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
Overlay histogram showing Hela cells stained with CSB-MA0157131A0m (red line). The cells were fixed with 70% Ethylalcohol (18h) and then permeabilized with 0.3% Triton X-100 for 2 min. The cells were then incubated in 1x PBS /10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (10µg/1*106cells) for 1 h at 4°C. The secondary antibody used was FITC goat anti-mouse IgG(H+L) at 1/200 dilution for 1 h at 4°C. Isotype control antibody (green line) was mouse IgG1 (10µg/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
NES Antibodies
NES for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-MA0157131A0m | NES Monoclonal Antibody | Human | ELISA, WB, IHC, IF, FC |
| CSB-PA094270 | NES Antibody | Human | ELISA,IHC |
| CSB-PA558433 | NES Antibody | Human | ELISA,IHC |
| CSB-PA137248 | NES Antibody | Human | ELISA,IHC |
| CSB-PA015713YA01HU | NES Antibody | Human | ELISA, IHC, IF |
| CSB-PA015713YB01HU | NES Antibody, HRP conjugated | Human | ELISA |
| CSB-PA015713YC01HU | NES Antibody, FITC conjugated | Human | |
| CSB-PA015713YD01HU | NES Antibody, Biotin conjugated | Human | ELISA |
NES Proteins
NES Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP015713RA CSB-EP015713RA CSB-BP015713RA CSB-MP015713RA CSB-EP015713RA-B |
Recombinant Rat Nestin (Nes), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NES Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP015713HU | Recombinant Human Nestin (NES), partial | Yeast |
| CSB-EP015713HU CSB-BP015713HU CSB-MP015713HU CSB-EP015713HU-B |
Recombinant Human Nestin protein (NES), partial | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NES Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP015713DIL CSB-EP015713DIL CSB-BP015713DIL CSB-MP015713DIL CSB-EP015713DIL-B |
Recombinant Danio rerio Nestin (nes), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NES Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP015713MO CSB-EP015713MO CSB-BP015713MO CSB-MP015713MO CSB-EP015713MO-B |
Recombinant Mouse Nestin (Nes), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NES Proteins for Mesocricetus auratus (Golden hamster)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP015713MRG CSB-EP015713MRG CSB-BP015713MRG CSB-MP015713MRG CSB-EP015713MRG-B |
Recombinant Mesocricetus auratus Nestin (NES), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NES Proteins for Drosophila melanogaster (Fruit fly)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP893810DLU CSB-EP893810DLU CSB-BP893810DLU CSB-MP893810DLU CSB-EP893810DLU-B |
Recombinant Drosophila melanogaster Transmembrane protein nessy (nes), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
