Mogat1
Mogat1，即糖基化磷酸化酶1，別名包括GLP-1 O-acyltransferase、GOPAT、MGAT1等。它是一種由MOGAT1基因編碼的酶，主要在小腸和胰腺等組織中表達。Mogat1的作用機制涉及催化GLP-1（胰高血糖素樣肽-1）的N-糖基化反應，這是GLP-1成熟過程中的關鍵步驟，影響其穩定性和生物活性。Mogat1參與了GLP-1的生物合成，GLP-1是一種重要的腸促胰島素激素，對調節血糖水平具有重要作用。Mogat1的功能異?？赡苡绊慓LP-1的產生和作用，進而影響胰島素分泌和血糖控制，是糖尿病研究和治療中的一個潛在靶點。
熱銷產品
MOGAT1 Antibody (CSB-PA836275LA01HU)
驗證數據
IHC image of CSB-PA836275LA01HU diluted at 1:300 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of CSB-PA836275LA01HU diluted at 1:300 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunofluorescence staining of HepG2 cells with CSB-PA836275LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Mogat1 Antibodies
Mogat1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA014710GA01HU | MOGAT1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA836275LA01HU | MOGAT1 Antibody | Human | ELISA, IHC, IF |
| CSB-PA836275LB01HU | MOGAT1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA836275LC01HU | MOGAT1 Antibody, FITC conjugated | Human | |
| CSB-PA836275LD01HU | MOGAT1 Antibody, Biotin conjugated | Human | ELISA |
Mogat1 Proteins
Mogat1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP836275HU1 CSB-EP836275HU1 CSB-BP836275HU1 CSB-MP836275HU1 CSB-EP836275HU1-B |
Recombinant Human 2-acylglycerol O-acyltransferase 1 (MOGAT1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF836275HU | Recombinant Human 2-acylglycerol O-acyltransferase 1 (MOGAT1) | in vitro E.coli expression system |
