MYCBP2
MYCBP2 is a protein in humans that is encoded by MYCBP2 gene. Atypical E3 ubiquitin-protein ligase which specifically mediates ubiquitination of threonine and serine residues on target proteins, instead of ubiquitinating lysine residues. Shows esterification activity towards both threonine and serine, with a preference for threonine, and acts via two essential catalytic cysteine residues that relay ubiquitin to its substrate via thioester intermediates. Interacts with the E2 enzymes UBE2D1, UBE2D3, UBE2E1 and UBE2L3. Plays a key role in neural development, probably by mediating ubiquitination of threonine residues on target proteins (Probable). Involved in different processes such as regulation of neurite outgrowth, synaptic growth, synaptogenesis and axon degeneration (By similarity). Required for the formation of major central nervous system axon tracts (By similarity). Required for proper axon growth by regulating axon navigation and axon branching acts by regulating the subcellular location and stability of MAP3K12/DLK (By similarity). Required for proper localization of retinogeniculate projections but not for eye-specific segregation (By similarity).
MYCBP2 Proteins
MYCBP2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP015272HU CSB-BP015272HU CSB-MP015272HU CSB-EP015272HU-B |
Recombinant Human Probable E3 ubiquitin-protein ligase MYCBP2 (MYCBP2), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP015272HU | Recombinant Human E3 ubiquitin-protein ligase MYCBP2 (MYCBP2), partial | E.coli |
MYCBP2 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP749258MO CSB-EP749258MO CSB-BP749258MO CSB-MP749258MO CSB-EP749258MO-B |
Recombinant Mouse Probable E3 ubiquitin-protein ligase MYCBP2 (Mycbp2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
